Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Antivirals > Flashcards

Antivirals Flashcards

1
Q

Inhibits guanine nucleotide synthesis by inhibiting inosine monophosphate dehydrogenase

A

Ribavirin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Tx for RSV, HepC

Toxicity

A

Ribavirin

Anemia, Teratogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Guanosine analog
Inhibits viral DNA polymerase
HSV/VZV thymidine kinase

A

Acyclovir, Famcyclovir, Valacyclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Tx for HSV, VZV

Toxicity

A

Acyclovir
Valacyclovir - better oral bioavailability
Famciclovir - herpes zoster
Crystalline neuropathy, acute renal failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Guanosine analog
Inhibits viral DNA polymerase
CMV viral kinase

A

Ganciclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tx for CMV

Toxicity

A

Ganciclovir
Valgancyclovir - better oral bioavailability
Leukopenia, neutropenia, thrombocytopenia, renal toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Viral DNA pol inhibitor

Binds to pyrophosphate binding site

A

Foscarnet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Tx CMV retinitis

Toxicity

A

Foscarnet

Nephrotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Protease inhibitors toxicity

A

Hyperglycemia, lipodystrophy, hematuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

NRTIs toxicity

A 
Bone marrow suppression
Peripheral neuropathy - nucleosides
Lactic acidosis - non nucleosides
Anemia - zdv
Pancraetitis - didanosine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

NNRTIs toxicity

A

Rash and hepatotoxicity
Vivid dreams, CNS symptoms - Efavirenz
Contraindicated in pregnancy - Delavirdine, Efavirenz

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Raltegravir toxicity

A

Hypercholesterolemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Enfuvirtide MOA

A

Binds gp41, inhibiting entry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Maravaroc MOA

A

Binds CCR , inhibiting interacts with gp120

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Raltegavir MOA

A

Reversible inhibits HIV integrase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

IFN beta

A

Multiple sclerosis

17
Q

IFN gamma

A

Chronic granulomatous disease

18
Q

IFN alpha

A 
Hep B and C
Kaposi sarcoma
Hairy cell leukemia
Condylomata acuminatum
Renal cell CA
Malignant melanoma
19
Q

Inhibits influenza neuraminidase

A

Zanamivir

Oseltamivir

Pharmacology (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions