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Boards > Drugs - FA > Flashcards

Drugs - FA Flashcards

1
Q

Leuprolide

A

GnRH analog

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2
Q

Anastrazole, Letrozole

A

Aromatase inhibitor

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3
Q

Exemestane

A

Aromatase inhibitor

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4
Q

Ulipristal

A

Progesterone antagonist

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5
Q

Terbutaline

A

Beta-2 agonist (relax uterus)

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6
Q

Ritodrine

A

Beta-2 agonist (relax uterus)

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7
Q

Danazol

A

Partial agonist at androgen receptors

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8
Q

Flutamide

A

Competitive inhibitor at androgen receptors

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9
Q

Ketoconazole (androgens)

A

Inhibits 17,20 desmolase (steroid synthesis)

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10
Q

Spironolactone (androgens)

A

Inhibits steroid binding, 17-alpha hydroxylase, and 17,20-desmolase

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11
Q

Minoxidil

Use?

A

Direct arteriolar vasodilator

Androgenic alopecia

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12
Q

1st generation antihistamines - inhibits what?

A

H1 (sedation), muscarinic, alpha-adrenergic

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13
Q

Guaifenesin

A

Expectorant - thins respiratory secretions

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14
Q

N-acetylcysteine (lungs)

A

Mucolytic - liquefies mucus by disrupting disulfide bonds

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15
Q

Dextromethorphan

Side effects?

A

Antitussive (antagonist at NMDA)

Serotonin syndrome, opioid effects

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16
Q

Pseudoephedrine vs. Phenylephrine - neuro

A

Pseudoephedrine - CNS agitation

17
Q

Bosentan

SE?

A

Antagonizes endothelin receptors

Hepatotoxic

18
Q

Epoprostenol, Iloprost - SEs (2)

A

Flushing, jaw pain

19
Q

LABAs - SEs (2)

A

Tremor, arrhythmia

20
Q

Fluticasone

A

Inactivate NF-kB (inhaled corticosteroid)

21
Q

Budesonide

A

Inhaled corticosteroid

22
Q

Ipratropium

A

Muscarinic antagonist (competitive)

23
Q

-lukast

Best for what?

A

CysLT1 receptor blockers

Aspirin-induced asthma

24
Q

Zileuton

SE?

A

5-lipoxygenase inhibitor

Hepatotoxic

25
Q

Theophylline - SEs

MOA

Blocks what?

A

Cardiotoxic (HTN, tachy), Neurotoxic (seizure)

PDE inhibitor

Blocks adenosine actions

26
Q

Bulimia nervosa

A

SSRIs

27
Q

GAD

A

SSRIs, SNRIs

28
Q

OCD

A

SSRIs, Venlafaxine, Clomipramine

29
Q

Panic disorder

A

SSRIs

30
Q

PTSD

A

SSRIs

31
Q

Tourette’s

A

Fluphenazine, Pimozide

Tetrabenazine

32
Q

Amphetamines - other uses besides ADHD (2)

A

Narcolepsy, Appetite control

33
Q

Trifluoperazine

A

Typical antipsychotic (high potency)

34
Q

Thioridazine

A

Typical antipsychotic (low potency)

35
Q

Lithium - side effects

A

LMNOP - movement (tremor), NDI, hypOthyroid, Pregnancy problems (Ebstein)

36
Q

NMS - symptoms

Treatment?

A

FEVER - fever, encephalopathy, vitals unstable, enzymes increased, rigidity

Dantrolene, D2 agonists (Bromocriptine)

37
Q

Serotonin syndrome - symptoms

Treatment?

A

AAA - activity (clonus, hyperreflexia), autonomic (hyperthermia, sweating, diarrhea), agitation

Cyproheptadine (5-HT2 antagonist)

38
Q

Risperidone - SE

A

Hyperprolactinemia (like typicals)

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