Drugs - FA

Question 1

Leuprolide

Answer 1

GnRH analog

Question 2

Anastrazole, Letrozole

Answer 2

Aromatase inhibitor

Question 3

Exemestane

Answer 3

Aromatase inhibitor

Question 4

Ulipristal

Answer 4

Progesterone antagonist

Question 5

Terbutaline

Answer 5

Beta-2 agonist (relax uterus)

Question 6

Ritodrine

Answer 6

Beta-2 agonist (relax uterus)

Question 7

Danazol

Answer 7

Partial agonist at androgen receptors

Question 8

Flutamide

Answer 8

Competitive inhibitor at androgen receptors

Question 9

Ketoconazole (androgens)

Answer 9

Inhibits 17,20 desmolase (steroid synthesis)

Question 10

Spironolactone (androgens)

Answer 10

Inhibits steroid binding, 17-alpha hydroxylase, and 17,20-desmolase

Question 11

Minoxidil

Use?

Answer 11

Direct arteriolar vasodilator

Androgenic alopecia

Question 12

1st generation antihistamines - inhibits what?

Answer 12

H1 (sedation), muscarinic, alpha-adrenergic

Question 13

Guaifenesin

Answer 13

Expectorant - thins respiratory secretions

Question 14

N-acetylcysteine (lungs)

Answer 14

Mucolytic - liquefies mucus by disrupting disulfide bonds

Question 15

Dextromethorphan

Side effects?

Answer 15

Antitussive (antagonist at NMDA)

Serotonin syndrome, opioid effects

Question 16

Pseudoephedrine vs. Phenylephrine - neuro

Answer 16

Pseudoephedrine - CNS agitation

Question 17

Bosentan

SE?

Answer 17

Antagonizes endothelin receptors

Hepatotoxic

Question 18

Epoprostenol, Iloprost - SEs (2)

Answer 18

Flushing, jaw pain

Question 19

LABAs - SEs (2)

Answer 19

Tremor, arrhythmia

Question 20

Fluticasone

Answer 20

Inactivate NF-kB (inhaled corticosteroid)

Question 21

Budesonide

Answer 21

Inhaled corticosteroid

Question 22

Ipratropium

Answer 22

Muscarinic antagonist (competitive)

Question 23

-lukast

Best for what?

Answer 23

CysLT1 receptor blockers

Aspirin-induced asthma

Question 24

Zileuton

SE?

Answer 24

5-lipoxygenase inhibitor

Hepatotoxic

Question 25

Theophylline - SEs

MOA

Blocks what?

Answer 25

Cardiotoxic (HTN, tachy), Neurotoxic (seizure)

PDE inhibitor

Blocks adenosine actions

Question 26

Bulimia nervosa

Answer 26

SSRIs

Question 27

GAD

Answer 27

SSRIs, SNRIs

Question 28

OCD

Answer 28

SSRIs, Venlafaxine, Clomipramine

Question 29

Panic disorder

Answer 29

SSRIs

Question 30

PTSD

Answer 30

SSRIs

Question 31

Tourette’s

Answer 31

Fluphenazine, Pimozide

Tetrabenazine

Question 32

Amphetamines - other uses besides ADHD (2)

Answer 32

Narcolepsy, Appetite control

Question 33

Trifluoperazine

Answer 33

Typical antipsychotic (high potency)

Question 34

Thioridazine

Answer 34

Typical antipsychotic (low potency)

Question 35

Lithium - side effects

Answer 35

LMNOP - movement (tremor), NDI, hypOthyroid, Pregnancy problems (Ebstein)

Question 36

NMS - symptoms

Treatment?

Answer 36

FEVER - fever, encephalopathy, vitals unstable, enzymes increased, rigidity

Dantrolene, D2 agonists (Bromocriptine)

Question 37

Serotonin syndrome - symptoms

Treatment?

Answer 37

AAA - activity (clonus, hyperreflexia), autonomic (hyperthermia, sweating, diarrhea), agitation

Cyproheptadine (5-HT2 antagonist)

Question 38

Risperidone - SE

Answer 38

Hyperprolactinemia (like typicals)