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OSCE > Drugs > Flashcards

Drugs Flashcards

1
Q

What blood monitoring do you need for methotrexate

A

FBC, LFTs U+Es
before starting, 2w until stable
then every 2-3m

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2
Q

What are the side effects of methotrexate?

A 
Alopecia
Headache
GI
Myelosuppresion
Liver imp
Pulmonary imp
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3
Q

What lifestyle advice do you give for methotrexate?

A 
no trying for kids/preg/BF
Fever - come in
Don't drink
SOB - come in
Flu jab
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4
Q

Contraindications to methotrexate?

A

Preg/BF/trying
infection
Liver imp

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5
Q

What monitoring do you need to do for lithium?

A

FBC, U+Es, LFTs, bHCG, ECG
Lithium - after 4d, then every week, then every 3m
TFTs, U+Es, Ca2+/6m

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6
Q

What are the side effects of lithium?

A 
GI
Metallic tast
Tremor
Water; thirst, polyuria, retention
Renal tox
DI
hypothryoid
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7
Q

What are the signs of lithium toxicity?

A

GI - vom, diarrhoea, anorexia

Neuro - ataxia, coordination, twitch/tremor, drowsy

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8
Q

Contraindications to lithium?

A 
Preg/BF
Heart disease
Bad renal disease
Addisons
Untreated hypothryoid
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9
Q

How to take bisphosphonates?

A

Full glass of water, don’t eat for 30 mins

Upright for 30 mins after

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10
Q

Side effects of bisphosphonates?

A

Headache
GI - heartburn, indigestion
Osteonecrosis of jaw

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11
Q

Contraindications to bisphosphonates

A

Preg
Dysphagia
Ulcers
Bad renal imp

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12
Q

How long do iron tablets take to work?

A

3-4w to replenish Hb (and help symptoms) but 4m total to replenish store

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13
Q

What are the side effects of SSRIs?

A

Weight gain
Drowsy
Headache
Nausea/diarrhoea

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14
Q

Side effects of atypical antiphyscotics?

A 
dopa - tardive dyskinesia, tremor
cholin - dry mouth, constipation
hist - drowsy, weight gain
adren - hypotensive
neuroleptic malignant syndrome
agranulocytosis
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15
Q

Risks/side effects of metformin

A

Weight loss
Nausea
GI
Lactic Acidosis

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16
Q

Contraindications to metformin

A

Renal imp
Low BI
Ketoacidosis

17
Q

Side effects of warfarin

A

Bleeding/bruising
Rash
Diarrhoea
Hair Loss

18
Q

What should you avoid w/ warfarin?

A 
Liver
Spinach
Cranberry
Alcohol binging/changing
NSAIDs/aspirin
19
Q

What monitoring do you need for statins?

A

LFT before, 3m, 12m

20
Q

Side effects of levodopa

A

Psychosis
N&V
Dyskinesia
Postural hypotension

21
Q

Contraindication to levodopa

A

Glaucoma

22
Q

Which factors do warfarin act on?

A

II, VII,IX,X both pathways

23
Q

What OTC med can you not have if on methotrexate?

A

NSAIDs - inhibit excretion

OSCE (20 decks)

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