Drugs Flashcards
give 2 examples of tricyclic antidepressants
amitriptyline
nortriptyline
tricyclic antidepressants
- indication
- moa
- side effects
depression, BMS
inhibit reuptake or serotonin and noradrenaline
dry mouth, drowsiness, constipation
give 2 examples of SSRIs
citalopram
sertraline
fluoxetine
SSRIs
- indication
- mechanism
- side effects
depression, PTSD
selectively inhibit reuptake of serotonin
dry mouth, constipation, dizziness,
give 2 examples of loop diuretics
furosemide
bumetanide
diuretics
- indication
- moa
- side effects
hypertension, oedema
inhibit resorption of sodium and therefore fluid in renal tubules
dizziness, electrolyte imbalance, fatigue, headache, nausea
name 2 examples of ACE inhibitors
ramipril
enalapril
lisinopril
ACE inhibitors
- indication
- MOA
- side effects
- hypertension, heart failure
- inhibit ACE i.e conversion of angiotensin 1 to angiotensin 2 so aldosterone production not stimulated
- dry mouth, dizziness, electrolyte imbalance, headache
name 2 examples of beta blockers
atenolol
nadolol
beta blockers MOA and indications
hypertension
angina
MIs
arrythmias
decrease heart rate by blocking affects of adrenaline
side effects of beta blockers
bradycardia
dizziness
peripheral coldness
headache
name 2 examples of calcium channel blockers
amlodipine
felodipine
diltiazem
indication and moa of calcium channel blockers
hypertension, angina, arrythmias
inhibit calcium entering cells of heart and bvs. (calcium is required for muscle contraction)
side effects of calcium channel blockers
dizziness, headache, nausea, palpitations, abdominal pain
name 2 statins
simvastatin
atorvastatin
fluvastatin
statins
- indications
- MOA
hypercholesterolaemia, atherosclerotic cardiovascular disease
inhibit enzymes involved in cholesterol synthesis, especially in the liver
side effects of statins
nausea, headache, constipation, arthralgia, thrombocytopenia
what type of drug is metformin
biguanide
what is metformin used to treat and what is its mechanism of action
used in type 2 diabetes
decreases gluconeogenesis (production of glucose) and increases peripheral utilisation of glucose
(requires some functioning pancreatic islet cells)
side effects of metformin
abdominal pain, diarrhoea, vit B12 deficiency, altered taste, decreased appetite
