Drug Treatment - MI

Question 1

what is the first line investigation in suspected ACS?

Answer 1

ECG

Question 2

what is the immediate management of an MI?

Answer 2

MONA + C

morphine (+anti-emetic) 
oxygen if hypoxic 
nitrates - GTN 
aspirin 300mg - chewed 
clopidogrel

Question 3

name three P2YI2 inhibitors

Answer 3

clopidogrel
ticagrelor
prasugrel

Question 4

what can be done to physically unblock the artery in MI?

Answer 4

PPCI

Question 5

when is thrombolysis done for MI?

Answer 5

if PPCI can’t be done within 120 minutes

Question 6

what thrombolytic drugs can be given for MI?

Answer 6

tenecteplase
alteplase
reteplase

Question 7

what drugs need to be administered alongside thrombolysis for it to be effective?

Answer 7

aspirin

clopidogrel

Question 8

what is the immediate management for an NSTEMI?

Answer 8

morphine
oxygen if hypoxic
SL GTN
aspirin 300mg

Question 9

what is the definitive management for an NSTEMI?

Answer 9

P2YI2 inhibitor
beta blocker
fondaparinux

Question 10

what drugs should MI patients be on after discharge?

Answer 10

long term aspirin 
ticagrelor 
ACEi or ARB
eplerenone
statin

Question 11

what is the MOA of aspirin?

Answer 11

thromboxane A2 inhibitor

Question 12

what is a possible side effect of ticagrelor?

Answer 12

dyspnoea

Question 13

when is prasugrel contraindicated?

Answer 13

previous stroke/TIA

not recommended >75 with low BMI