Drug Therapy

Question 1

Explain a typical antipsychotic.

Answer 1

-chlorpromazine
-Dopamine antagonist and reduces brain
-Bind to the D2 receptors in the post synaptic neuron
-reduce dopamine action
-reduce positive symptoms of schiz
-sedative

Question 2

Explain atypical antipsychotic.

Answer 2

-clozapine
-acts upon both Dopamine and Seritonin
-bind on the D2 receptor sites in PSN reduce ps of schz
-agonist upon seritonin recpetor sites increasing levels of seritonin
-reduce negative symptoms improve moods and reduce anxiety

Question 3

What are the evaluations?

Answer 3

-RTS, Thornley et al
-little motivation is required
-Negative side effects

Question 4

Explain teh RTS?

Answer 4

-meta analysis of 13 studies
-1121 ppt investigating chlorpromazine against a placebo
-typical antipsychotic associated with overall better functioning and reducing severe symptoms
-meltzer clozapine effective in 30-50% resistant cases
-increasing validity

Question 5

Little motivation required?

Answer 5

-only have to take a tablet to rec=duce there symptoms
-unlike CBT