Drug quiz 8 Flashcards
Calcium Chloride Mechanism of Action
Replacement of elemental calcium-increases myocardial contractility and ventricular automaticity
Calcium Chloride Drug Classification
Mineral / Electrolyte
Calcium Chloride Pharmacokinetics
Onset of Action=Immediate
Peak Effects=Unknown
Duration of Effect=Varies
Half-Life=N/A
Calcium Chloride Indications/Field Use
Acute hyperkalemia
Acute hypocalcemia
Ca channel blocker toxicity
Crush Syndrome
Hypermagnesemia
Abd muscle spasm from Brown Recluse Spider or Man of War Jellyfish
Cardiac Arrest 2nd to suspected hyperkalemia or known dialysis pt
Calcium Chloride Contraindications
V-fib
Hypercalcemia
Calcium Chloride Side Effects/Adverse Reaction
Bradycardia, dysrhythmias, N+V, syncope, cardiac arrest
Calcium Chloride Dose
Adult: 8-16mg/kg IV, IO or 500-1000mg IV, IO
Pedi: 20mg/kg slow IVP (IO)
Calcium Chloride Precautions
Can cause tissue necrosis at injection site, ensure patent IV line
Caution pt taking digitalis, may precipitate digatalis toxicity
Calcium Chloride Drug-Drug Interactions
Forms PPT wih NaHCO3, flush tubing between administration
Can cause digitalis toxicity when given to pt taking digitalis
Sodium Bicarbonate Drug Classification
Alkalinizing agent / electrolyte
Sodium Bicarbonate Mechanism of Action
Alkaline electrolyte that buffers excess H+
Cabonic Acid-Bicarbonate Buffer System
Sodium Bicarbonate Pharmacokinetics
Onset of action=Immediate
Peak Effects= <15 minutes
Duration of Effect=1-2hours
Half-Life=N/A
Sodium Bicarbonate Indications/Field Use
Metabolic acidosis secondary to overdose
Cardiac arrest with known or suspected hyperkalemia
Sodium Bicarbonate Contraindications
Respiratory Acidosis
Sodium Bicarbonate Side Effects/Adverse Reactions
None in emergency setting
Sodium Bicarbonate Dose
1mEq/kg (initial) IV, IO
Sodium Bicarbonate Precautions
Causes metabolic alkalosis when administered in large quantities
Sodium Bicarbonate Drug-Drug Interactions
Deactivates catecholamines and vasopressors, reacts with CaCl2 to form PPT (in IV tuping)