Drug Profiles Flashcards
Calcium Chloride Names:
Generic -
Brand -
Class -
Calcium chloride 10%
Calcium chloride
Electrolyte
Calcium Chloride:
Mechanism of Action-
Increases serum calcium ion levels
- Stimulates release of catecholamines - Increases muscle force of contraction (inotrope) - May enhance ventricular automaticity
Calcium Chloride:
Indications of Field Use-
- Calcium channel blocker
- Hypocalcemia
- Pretreatment for Verapamil
- Hyperkalemia
Calcium Chloride:
Adult Dosage-
-All dosages are IV push
-Calcium channel blocker OD, Hypocalcemia,
Hypermagnesemia
-Calcium 10% 0.5-1.0 gram (5-10ml) IV push. May repeat
in 10 min.
-Pretreatment for Verapamil
-Calcium Chloride 10% 3ml may repeat once
-Hyperkalemia
-1 Gram IV/IO over 5 minutes, do not exceed
1ml/min
Calcium Chloride:
Peds Dosage-
-Calcium chloride 10% 0.2 mg/kg very slow IV push once
Calcium Chloride:
Contraindications-
-Digitalis, Lanoxin, Digoxin (may cause asystole or
digitalis toxicity)
-Hypercalcemia
-Suspected severe hypokalemia
Calcium Chloride:
Drug Interactions-
-Digitalis, Lanoxin, Digoxin may cause asystole or dig
toxicity
-Do not give in same IV as another drug unless line
flushed well.
Calcium Chloride:
Side Effects-
- Bradycardia
- Asystole
- Tissue necrosis if infiltrates
Magnesium Sulfate names:
Generic name-
Brand name-
Class-
- magnesium sulfate
- Magnesium Sulfate
- Electrolyte, tocolytic
Magnesium Sulfate:
Mechanism of Action-
Essential to enhance intracellular potassium
replenishment
-Important role on neuromechanical transmission and muscular excitability
-Decreases myocardial irritability and neuromuscular irritability
-CNS depressant effective in the management of seizures from eclampsia
Magnesium Sulfate:
Indications and Field Use-
- Severe bronchospasm refractory to inhaled B2 agonist
- Torsades de pointes
- Hypomagnesemia
- Refractory VFib/Pulseless VTach after antiarrhythmics
- Pregnancy induced hypertension
- Pre-eclampsia and/or eclampsia
Magnesium Sulfate:
Dosage-
-All dosages diluted. Routes: IV/IO slow push IV
infusion
Magnesium Sulfate:
Dosage Adult-
-Cardiac arrest: VFib/pulseless VTach/Torsades de
pointes
-2 grams diluted in 10cc NS IV over 2 minutes
-Torsades de Pointes with pulse
-2 grams in 50 or 100 cc NS bag infusion over 5-10
minutes
-Severe bronchospasm refractory to inhaled B2 agonist
-2 grams in 50 or 100 cc NS bag infusion over 10
minutes
-Pre-eclampsia and/or eclampsia
-4-6 grams in 50 or 100 cc NS bag infusion over 20
minutes
Magnesium Sulfate:
Dosage Peds-
-Severe bronchospasm refractory to inhaled B2 agonist
Magnesium Sulfate:
Contra Indications-
- Hypermagnesemia
- Impaired renal function=relative
- Heart Blocks