drug main uses (Beta Blockers) Flashcards

1
Q

Acebutolol (Sectral)

A

B1 (Cardioselective)

Competitive antagonism of B1 receptor

Lipid sol: L
partial agonist: yes
membrane stabilizing: yes

Decreased HR, Contractility, Automaticity, Conduction velocity; Decreased myocardial O2 deficit and cardiac output (decreased rate and contractility); Decreased renin secretion (B1 in JG Cells); Protection from thyroid storm and pheochromocytoma.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Atenolol (Tenormin)

Esmolol (Brevibloc)

A

B1 (Cardioselective)

Competitive antagonism of B1 receptor

Lipid sol: L
partial agonist: no
membrane stabilizing: no

Decreased HR, Contractility, Automaticity, Conduction velocity; Decreased myocardial O2 deficit and cardiac output (decreased rate and contractility); Decreased renin secretion (B1 in JG Cells); Protection from thyroid storm and pheochromocytoma.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Metoprolol (Lopressor, Toprol-XL)

A

B1 (Cardioselective)

Competitive antagonism of B1 receptor

Lipid sol: M
partial agonist: no
membrane stabilizing: yes

Decreased HR, Contractility, Automaticity, Conduction velocity; Decreased myocardial O2 deficit and cardiac output (decreased rate and contractility); Decreased renin secretion (B1 in JG Cells); Protection from thyroid storm and pheochromocytoma.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Nadolol (Corgard)

A

B1 & B2 (Non-selective)

Competitive antagonism of B1 & B2 receptors

Lipid sol: L
partial agonist: no
membrane stabilizing: no

Enhancement of B1 agonist effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Pindolol

A

B1 & B2 (Non-selective)

Competitive antagonism of B1 & B2 receptors

Lipid sol: M
partial agonist: yes
membrane stabilizing: yes

Enhancement of B1 effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Propanolol (Inderal-LA)

A

B1 & B2 (Non-selective)

Competitive antagonism of B1 & B2 receptors

Lipid sol: H
partial agonist: no
membrane stabilizing: yes

Enhancement of B1 effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Timolol (Timoptic)

A

B1 & B2 (Non-selective)

Competitive antagonism of B1 & B2 receptors

Lipid sol: M
partial agonist: no
membrane stabilizing: no

Treats glaucoma by decreasing aqueous humor production and thus IOP.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Labetalol (Trandate)

A

B-blocker and a-blocker

Rapid decrease of arterial pressure from B antagonism and a-antagonist-induced decrease in peripheral arterial resistance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly