drug main uses (Beta Blockers) Flashcards
Acebutolol (Sectral)
B1 (Cardioselective)
Competitive antagonism of B1 receptor
Lipid sol: L
partial agonist: yes
membrane stabilizing: yes
Decreased HR, Contractility, Automaticity, Conduction velocity; Decreased myocardial O2 deficit and cardiac output (decreased rate and contractility); Decreased renin secretion (B1 in JG Cells); Protection from thyroid storm and pheochromocytoma.
Atenolol (Tenormin)
Esmolol (Brevibloc)
B1 (Cardioselective)
Competitive antagonism of B1 receptor
Lipid sol: L
partial agonist: no
membrane stabilizing: no
Decreased HR, Contractility, Automaticity, Conduction velocity; Decreased myocardial O2 deficit and cardiac output (decreased rate and contractility); Decreased renin secretion (B1 in JG Cells); Protection from thyroid storm and pheochromocytoma.
Metoprolol (Lopressor, Toprol-XL)
B1 (Cardioselective)
Competitive antagonism of B1 receptor
Lipid sol: M
partial agonist: no
membrane stabilizing: yes
Decreased HR, Contractility, Automaticity, Conduction velocity; Decreased myocardial O2 deficit and cardiac output (decreased rate and contractility); Decreased renin secretion (B1 in JG Cells); Protection from thyroid storm and pheochromocytoma.
Nadolol (Corgard)
B1 & B2 (Non-selective)
Competitive antagonism of B1 & B2 receptors
Lipid sol: L
partial agonist: no
membrane stabilizing: no
Enhancement of B1 agonist effects
Pindolol
B1 & B2 (Non-selective)
Competitive antagonism of B1 & B2 receptors
Lipid sol: M
partial agonist: yes
membrane stabilizing: yes
Enhancement of B1 effects
Propanolol (Inderal-LA)
B1 & B2 (Non-selective)
Competitive antagonism of B1 & B2 receptors
Lipid sol: H
partial agonist: no
membrane stabilizing: yes
Enhancement of B1 effects
Timolol (Timoptic)
B1 & B2 (Non-selective)
Competitive antagonism of B1 & B2 receptors
Lipid sol: M
partial agonist: no
membrane stabilizing: no
Treats glaucoma by decreasing aqueous humor production and thus IOP.
Labetalol (Trandate)
B-blocker and a-blocker
Rapid decrease of arterial pressure from B antagonism and a-antagonist-induced decrease in peripheral arterial resistance