Drug interactions

Question 1

Warfarin

Answer 1

• Sulfa
• Quinolones
• Macrolides
• clarithyomycin
• NSAIDs
• Phenytoin

all increase INR/Bleeding

Question 2

Sildenafil (Viagra)

Answer 2

• Nitrates - hypotension

- Antifungals - increase levels

Question 3

Statins

Answer 3

Niacin
erythromycin

increase risk of rhabdo

Question 4

SSRI’s

Answer 4

St. John Wort (serotonin syndrome)
Triptans ( increase levels )
TCAs

Question 5

Oral contraceptives ( transdermal patch (ortho era) and nuvaring

Answer 5

rifampin
ampicillin
tetracycline

• lowers effectiveness of brith control -

Question 6

Ace/ARB

Answer 6

Potassium supplements
spironolactone
— hyperkalemia

Question 7

KEY for Cephalsporins

Answer 7

Keflex, Ceftriazone

people who are allergic to penicillin may be allergic to cephs

considered beta-lactam

Question 8

Key for Pencillins

Answer 8

strep throat

considered beta lactam

Question 9

Keys for Macrolides

Answer 9

erythromycin, azothromycin

A ton of drug/ drug interactions

increase risk of arrhythmias, prolong QT, GI upset

Question 10

keys for Tetraclyclines

Answer 10

tetracyline, doxycline,

stains tooth enamel

do not combine with antacids, iron

Question 11

keys for sulfonamides

Answer 11

Trimethroprim-sulfamethazole

avoid in G6PD ( causes jaundice )

dont give in 1st and third trimesters

Question 12

keys Flouroquinolones

Answer 12

cipro, floxin

dont combine with antiacids or iron

HYPOglycemia, CNS agitation, tendonitis, awhiles tendon rupture