Drug Formulations and Patient Counseling - Quiz 1 Flashcards
What are the benefits of using long duration meds?
Reduces peaks and side effects
Examples of OROS?
- Concerta
- Cardura XL
- Procardia XL
- Delzicol
Counseling on long acting capsules and tablets?
- Dont crush or chew
- Some capsules can be sprinkled on food but do not chew contents
- Cut on score lines (Toprol XL, carbidopa/levodopa ER)
Benefits of liquid oral solutions/suspensions?
Useful for children and difficulty swallowing
Counseling for suspensions?
Shake before use
Examples of chewable tablet?
Montelukast (Singular)
Lamotrigine (Lamictal)
Benefits of using chewables?
Used in children who are unable to swallow tablets
What are lozenges/troches used for?
Conditions of oral mucosa
Benefits of using ODT?
- Patient with dysphagia
- Children who are unable to swallow
- Non-adherence (cheeking)
Benefits of SL or buccal methds?
- Same benefits of ODT
- Onset of action is faster
- Less gut degradation and first pass metabolism
How can you administer singulair granules?
In applesauce, carrots, rice, ice cream
How can you administer Vyvanse granuales?
Water, yogurt, orange juice
Counseling points for granuales, powders, capsules?
- Don’t chew pellets
- Don’t let mixture sit too long (entire mixtre should be ingested)
- Don’t add to anything warm or hot
Types of sweeteners?
- Sorbitol
- Phenylalanime (aspartame)
- Lactose
Formulations containing phenylalanime?
ODT, chewable, granules
CI of phenylalanine?
Phenylketonuria (PKU): genetic deiciency in enzyme that degrades phenylalanine
ODT Counseling points?
- Tablets are friable and you should peel back the foil
- Place tablet on tongue and dissolve in seconds
What medications can be self-administered?
SC:
* Eanercept (Enbrel)
* Teriparatide (Forteo)
* Sumatriptan (Imitrex)
* Insulins, GLP1 agonists
* Enoxaparin (Lovenox)
* Naloxone
* Methotrexate (Otrexup)
Injection counseling?
- Warfarin
- Prepare injection
- Select and clean site
- Inject
- Discard syringe
- Inject at least 1 inch away from previous site
- Only use needle once
- Don’t rub anticoag injection (Lovenox, fondaparinux)
- Don’t heat up cold injections
- DOn’t use if discolored
- EpiPen can be rubbed
How to store/handle biologics?
Easily denature:
* Don’t shake
* Don’t expose to extremem temperatures
Application site of Xulane? Frequency?
Back, abdomen, arm, buttocks
Weekly (3 wks on, 1 wk off)
Application site of daytrana? Frequncy
Hip
QAM, remove at PM
Frequency of NicoDerm
QD
Lidoderm frequency?
12 hrs on, 12 hrs off
Oxytrol application site? Frequency?
Abdomen, hip, buttock
Twice weekly
Vivelle dot application site? Frequency?
Lower abdomen, buttock
Twice weekly
Transderm-Scop site? Frequency?
Behind the ear
Q72H
Fentanyl patch frequency?
72H
What patches can be cut?
Lidoderm and Qutenza
Why avoid heat on patches?
Increases absorption
What to do if patient has skin irritation?
- Don’t apply on irritated skin
- Alternate the site
- Skin should not be shaved
What patches should be taken off before MRI? Why?
- Clonidine (Catapress-TTS)
- Rotigotine (Neupro)
- Scopolamine (Transderm-Scop)
- Testosterone (Androderm)
Contains metal and can burn the skin
Patches that can have adhesive dressing?
Fentanyl, Butrans
What patch comes with its own adhesive cover?
Catapres-TTS
Frequency of Catapess-TTS?
Weekly
What patches need to be disposed of in the toilet?
Hihly potent narcotic patches: Fentanyl, Butrans, Daytrana
Benefits of topicals?
Local effects and decreased systemic side effects
Benefits of nasal sprays?
- Faster onset
- Useful for acute conditions
- Bypass gut absorptin and first pass-metabolism
Counseling for nasal spray?
Before use:
1. Shake bottle gently
2. Prime the pump before first use
3. Blow your nose
Using the spray:
1. Close one nostril and insert applicator
2. Start to breath in through your nose, and press firmly and quickly down
3. Breathe out through mouth
4. wipe applicatory
5. Don’t blow nose right away
Counseling for eye drops?
- Shake a few times
- Look up and pull down lower lid
- Apply drop in space between lower lid and eye
- Close eye and press finger between eye and top of nose for 1 min