Asthma - Quiz 3 Flashcards
What is asthma?
Inflammation and bronchoconstriction cause airway obstruction causing expiratory airflow limitation
What are the common triggers for asthma?
- Pollution
- Cigarettes
- Cold air
- Pets
- Dust, pollen, roaches
- Perfume
- Drugs (Aspirin, NSAIDs, non-selective beta blockers)
What is FEV1?
How much air can be forcefully exhaled in one second
What is FVC?
The max volume of air exhaled after taking a deep breath
What is FEV1/FVC?
The percentage of total air capacity that can be forcefully exhaled in one second
What is the asthma diagnostic criteria?
- Measure baseline FEV1 with spirometry
- Give albuterol
- Measure post-bronchodilator FEV1
An FEV1 increase >12% post-bronchodilator is consistent with asthma diagnosis (reversible)
Guidelines for asthma tx?
GINA
Initial asthma tx step 1?
Daytime sx: <2/month
Night sx: none
Initial asthma tx step 2?
Daytime sx: <2/month but <4-5 d/wk
Night sx: none
Initial asthma tx step 3?
Daytime sx: Most days
Night sx: <1/wk
Initial asthma tx step 4?
Daytime sx: Daily
Night sx: ≥1/wk
How often are follow ups?
2-6 wks
How do you control RF?
- Avoid smoking
- Annual flu vaccine
- Pneumococcal and COVID vaccines
- Allergen test
What are relievers for ?
Acute sx
What are the preferred reliever regimens?
low dose ICS+formoterol
SABA
Types of relievers?
- low dose ICS+formoterol
- SABA
- Systemic steroids
- Inhaled epinephrine
- SAMA
Reliever that quickly reverses bronchoconstriction?
SABA
Agents that are used for exacerbations?
low dose ICS+formoterol
PO systemic steroids
What is first line controllers?
ICS
What agent is commonly used in children
LTRAs
Examples of SABA?
- Albuterol
- Levalbuterol
- Epinephrine
Albuterol
ProAir, Ventolin, Proventil
Levalbuterol
Xopenex
LABA example?
Salmeterol
Salmeterol
Serevent Diskus
ADRs of SABAs?
- Nervousness
- Tremor
- Tachycardia
- Palpitations
- Cough
- Hyperglycemia
- Low K
How many inhalations are in albuterol?
Albuterol: 200 inh/canister
Ventolin: 200 or 60 inh/canister
BBW of LABA?
- Increased asthma deaths without ICS
- Increased asthma hospitalization (pediatric and adolescents)
Beclomethasone
QVAR Redihaler
Budesonide
Pulmicort