Drug development workshop Flashcards
1
Q
explain the link between EGFR and head and neck cancer
A
EGF receptor acitvates cyclin D and other pathways which result in cell proliferation
2
Q
phosphorylation can switch protein activity on or off mainly?
A
on
3
Q
what are the 2 forms of entry for covid into a human cell?
A
direct fusion
endosomal
4
Q
direct fusion -> entry of covid into a human cell
Cleavage of ?? by ?
Binding to ? receptor
Processing by ?
Diffusion
A
spike protein
Furin
ACE2
TMPRSS2
5
Q
A