Drug Deck - Assignment Flashcards
Acetylsalicylic Acid (Aspirin)
Class:
- Platelet aggregator inhibitor
- Nonsteroidal anti-inflammatory drug (NSAID)
Action:
- Blocks formation of thromboxane A2 which prevents platelets from clumping (aggregating)
- Prevents clots from forming
Indications:
- Chest pain and/or signs and symptoms suggestive of the acute coronary syndrome
- ECG waveforms suggestive of the acute coronary syndrome
Adenosine (Adenocard)
Class:
- Antidysrhythmic
Action:
- Slows atrioventricular conduction
Indications:
- Supraventricular tachycardia
- Wolff-Parkinson-White (WPW) syndrome
- Monomorphic wide-complex tachycardia
Albuterol Sulfate (Proventil, Ventolin)
Class:
- Sympathomimetic
- Bronchodilator
- Beta2 agonist
Action:
- Relaxes bronchial smooth muscle resulting in bronchodilation
Indications:
- Asthma
- Bronchospasm associated with chronic bronchitis and emphysema
- Hyperkalemia
Amiodarone (Cordarone)
Class:
- Antidysrhythmic
Action:
- Blocks sodium, potassium, and calcium channels
- Prolongs the action potential and repolarization
- Slows the sinus rate
- Increases the PR interval and QT interval
Indications:
- Ventricular fibrillation
- Pulseless ventricular tachycardia
- Wide complex tachycardia
Atropine Sulfate
Class:
- Anticholinergic
- Parasympathetic blocker
- Antidote
Action:
- Blocks the action of acetylcholine
- Increases the heart rate
- Reverses symptoms of cholinergic poisoning
Indications:
- Hemodynamically significant bradycardia
- Organophosphate poisoning
- Carbamate poisoning
- Nerve agent exposure
Calcium Chloride
Class:
- Electrolyte
Action:
- Increases intracellular calcium levels
- Increases myocardial contractility
Indications:
- Acute hypocalcemia
- Calcium channel blocker overdose
- Beta-blocker overdose
- Hyperkalemia
Charcoal Activated (without Sorbitol)
Class:
- Adsorbent
Action:
- Adsorbs (binds with) and inactivates toxic substances in the gastrointestinal tract
Indications:
- Oral poisonings
- Oral overdoses
Dexamethasone Sodium Phosphate (Decadron)
Class:
- Corticosteroid
- Glucocorticoid
- Anti-inflammatory
Action:
- Suppresses acute and chronic inflammation
- Produces immunosuppressive effect
- Stabilizes cellular membranes
Indications:
- Acute exacerbation of
- Asthma
- Chronic bronchitis
- Emphysema
- Reactive airway conditions
- Anaphylaxis
Dextrose (50%)
Class:
- Carbohydrate
- Antihypoglycemic
Action:
- Increases the glucose levels in the blood
Indications:
- Hypoglycemia
- Unconsciousness of unknown etiology
Diazepam (Valium)
Class:
- Benzodiazepine
- Anticonvulsant
- Sedative
- Hypnotic
Action:
- Produces sedation by acting on the limbic system, the thalamus, and hypothalamus
- Binds to gamma-amino butyric acid (GABA) benzodiazepine receptors in the brain
- Raises the seizure threshold
- Produces tranquilizing (antianxiety) effect on the central nervous system
Indications:
- Seizure activity
- Status epilepticus
- Procedural sedation for intubation and cardioversion
- Chemical restraint for agitated (excited) delirium
- Delirium tremens
Diltiazem (Cardizem)
Class:
- Calcium channel blocker
- Antidysrhythmic
Action:
- Slows extracellular calcium ion influx across myocardial cell membranes
- Slows conduction through the sinoatrial node and atrioventricular node
- Slows ventricular conduction rates in atrial fibrillation and atrial flutter
Indications:
- Atrial fibrillation with rapid ventricular rate
- Atrial flutter with rapid ventricular rate
- Supraventricular tachycardia second-line to administration of adenosine
Diphenhydramine HCL (Benadryl)
Class:
- Antihistamine
- Anticholinergic
Action:
- Blocks H1 histamine receptors
- Reverses phenothiazine reaction with extrapyramidal symptoms
Indications:
- Allergic reaction
- Anaphylaxis
- Phenothiazine reaction with extrapyramidal symptoms
Dopamine (Intropin)
Class:
- Sympathomimetic
- Vasopressor
Action:
- Increases the heart rate
- Increases the force of myocardial contractility
- Increases the blood pressure
- Increases preload
Indications:
- Cardiogenic shock
- Hemodynamically significant bradycardia
- Hemodynamically significant hypotension
Epinephrine HCL
Class:
- Sympathomimetic
Action:
-
Alpha-adrenergic response
- Vasoconstriction
-
Beta1-adrenergic responses
- Increases the heart rate
- Increases myocardial contractility
-
Beta2-adrenergic response
- Relaxes bronchial smooth muscle resulting in bronchodilation
- Blocks histamine receptors
Indications:
- Cardiac arrest
- Asystole
- Pulseless electrical activity
- Ventricular fibrillation
- Pulseless ventricular tachycardia
- Hemodynamically significant hypotension from a cause other than hypovolemia
- Asthma
- Bronchospasm associated with chronic bronchitis and emphysema
Etomidate (Amidate)
Class:
- Anesthesia induction agent
- Hypnotic
- Sedative
Action:
- Produces depression of the central nervous system
- Produces anesthesia
Indications:
- Procedural sedation for intubation
Fentanyl Citrate (Sublimaze)
Class:
- Narcotic analgesic
- Narcotic agonist
Action:
- Alleviates pain by depressing the central nervous system
- Depresses respiratory centers in the brainstem
- Decreases venous return to the heart
- Decreases preload
- Decreases afterload
Indications:
- Moderate to severe pain
- Procedural sedation including intubation
Furosemide (Lasix)
Class:
- Diuretic
Action:
- Inhibits the reabsorption of sodium and chloride in the kidneys
- Increases output of urine
Indications:
- Pulmonary edema
- Congestive heart failure
Glucagon (GlucaGen)
Class:
- Hyperglycemic
- Pancreatic hormone
Action:
- Converts glycogen to glucose
- Increases glucose levels in the blood
- Increases the force of myocardial contractility
- Increases the heart rate
Indications:
- Hemodynamically significant hypoglycemia
- Beta-blocker overdose
Ipratropium Bromide (Atrovent)
Class:
- Anticholinergic
- Bronchodilator
Action:
- Blocks acetylcholine receptors
- Dilates the larger airways resulting in bronchodilation
Indications:
- Asthma
- Bronchospasm associated with chronic bronchitis and emphysema
Ketamine (Ketalar)
Class:
- Sedative
- Anesthetic
- Analgesic
Action:
- Blocks pain receptors
- Produces a dissociative state
- Produces anesthesia
Indications:
- Procedural sedation for intubation
Lidocaine (Xylocaine)
Class:
- Antidysrhythmic
Action:
- Suppresses ventricular ectopic activity
- Increases the threshold of ventricular fibrillation
Indications:
- Ventricular fibrillation
- Ventricular tachycardia
- Ventricular dysrhythmias
- Frequent premature ventricular complexes and couplets
- Monomorphic and polymorphic wide-complex tachycardia
Lorazepam (Ativan)
Class:
- Benzodiazepine
- Anticonvulsant
- Sedative
- Hypnotic
Action:
- Produces sedation by acting on the limbic system, the thalamus, and cortex
- Binds to gamma-amino butyric acid (GABA) benzodiazepine receptors in the brain
- Raises the seizure threshold
- Exerts tranquilizing action (antianxiety effect) on the central nervous system
Indications:
- Seizure activity
- Status epilepticus
- Procedural sedation including intubation and cardioversion
- Chemical restraint for agitated (excited) delirium
Magnesium Sulfate
Class:
- Electrolyte
- Anti-inflammatory
- Tocolytic (labor suppressant)
Action:
- Decreases ventricular irritability
- Decreases release of acetylcholine that inhibits muscular excitability
- Causes uterine relaxation
- Relaxes bronchial smooth muscle resulting in bronchodilation
Indications:
Seizures caused by toxicity of pregnancy (toxemia)
Pregnancy induced hypertension (pre-clampsia and eclampsia)
Pre-term labor
Torsades de pointes (polymorphic ventricular tachycardia)
- Ventricular fibrillation and pulseless ventricular tachycardia refractory to amiodarone or lidocaine
- Reactive airway conditions including bronchoconstriction and bronchospasm
Methylprednisolone Sodium Succinate (Solu-Medrol)
🫁 😛 ️🔥
Class:
- Corticosteroid
- Glucocorticoid
- Anti-inflammatory
Action:
- Suppresses acute and chronic inflammation
- Produces immunosuppressive effect
- Stabilizes cellular membranes
Indications:
- Acute exacerbation of
- Asthma
- Chronic bronchitis
- Emphysema
- Reactive airway conditions
- Anaphylaxis
- Burns involving the airway
Midazolam (Versed)
Class:
- Benzodiazepine
- Anticonvulsant
- Sedative
- Hypnotic
Action:
- Produces sedation by acting on the limbic system, the thalamus, and hypothalamus
- Binds to gamma-amino butyric acid (GABA) benzodiazepine receptors in the brain
- Raises the seizure threshold
- Produces tranquilizing (antianxiety) effect on the central nervous system
Indications:
- Seizure activity
- Status epilepticus
- Procedural sedation for intubation and cardioversion
- Chemical restraint for agitated (excited) delirium
Morphine Sulfate
Class:
- Narcotic analgesic
- Narcotic agonist
Action:
- Alleviates pain by depressing the central nervous system
- Depresses brainstem respiratory centers
- Decreases venous return to the heart
- Decreases preload
- Decreases afterload
Indications:
- Moderate to severe pain
- Chest pain and/or signs and symptoms suggestive of the acute coronary syndrome
- Acute cardiogenic pulmonary edema
Naloxone (Narcan)
Class:
Narcotic antagonist
Action:
- Acts as a competitive antagonist at opiate receptors in the central nervous system
- Reverses the effects of narcotics and synthetic analgesic drugs
- Central nervous system depression
- Respiratory depression
- Respiratory arrest
Indications:
- Narcotic and synthetic drug overdoses
- morphine
- heroin
- oxycodone
- methadone
- codeine
- meperidine
- fentanyl
- hydrocodone
- hydromorphone
- Unconsciousness of unknown etiology
Nitroglycerine (NitroStat, NitroQuick, NitroLingual, NitroDur)
Class:
- Vasodilator
- Antianginal
- Nitrate
Action:
- Relaxes vascular smooth muscle
- Dilates coronary arteries resulting in increased blood flow to the myocardium
- Decreases workload on the heart
- Decreases myocardial oxygen demand
- Decreases preload
- Decreases afterload
Indications:
- Chest pain and signs/symptoms suggestive of the acute coronary syndrome
- Congestive heart failure with pulmonary edema
Nitrous Oxide 50% (Nitronox)
Class:
- Inhaled analgesic
Action:
- Alleviates pain by depressing the central nervous system
Indications:
- Moderate to severe pain due to musculoskeletal trauma and burns
Ondansetron (Zofran)
Class:
- Antiemetic
Action:
- Blocks serotonin 5-HT3 receptor sites in the central nervous system
- Inhibits nausea and vomiting
Indications:
- Nausea and vomiting
Oral Glucose (Glutose, Insta-Glucose)
Class:
- Carbohydrate
- Hyperglycemic
Action:
- Increases the glucose levels in the blood
Indications:
- Hypoglycemia
Oxygen (O2)
Class:
- Natural atmospheric gas
Action:
- Reverses hypoxia
- Increases arterial oxygen concentration
- Increases hemoglobin saturation
- Increases tissue oxygenation
Indications:
- Hypoxia
- Suspected hypoxia
Oxytocin (Pitocin)
Class:
- Pituitary hormone
- Uterine stimulant
Action:
- Increases the force and frequency of uterine contraction
Indications:
- Postpartum hemorrhage following delivery of the newborn and placenta
Phenylephrine (Neo-Synephrine®)
Class:
- Topical vasoconstrictor
Action:
- Vasoconstricts blood vessels in the nasal passages
- Reduces the risk of bleeding during insertion of a nasotracheal tube
Indications:
- Administered prior to insertion of a nasotracheal tube
Sodium Bicarbonate (Lifeshield)
Class:
- Alkalizing agent
Action:
- Buffers excess acid (H+)
- Increases the pH
Indications:
- Metabolic acidosis in these conditions
- Salicylate overdose
- Tricyclic antidepressant overdose
- Hyperkalemia
- Pre-existing or known metabolic acidosis
- Acidosis refractory to effective ventilation
- Prolonged cardiac arrest
Succinylcholine (Anectine®)
Class:
- Neuromuscular blocking agent
- Paralytic
Action:
- Inhibits neuromuscular transmission resulting in temporary paralysis
Indications:
- Procedural adjunct for intubation
Thiamine (Vitamin B1) [Betalin]
Class:
Vitamin
Action:
Metabolizes carbohydrates
Indications:
- Delirium tremens
- Wernicke encephalopathy
- Korsakoff syndrome
- Unconsciousness of unknown etiology
- Alcoholism
- Malnourishment
Vasopressin (Pitressin®)
Class:
- Vasopressor
Action:
- Produces vasoconstriction
Indications:
- Cardiac arrest
- Ventricular fibrillation
- Pulseless ventricular tachycardia
- Asystole
- Pulseless electrical activity
Verapamil (Isoptin, Calan)
Class:
- Calcium channel blocker
- Antidysrhythmic
Action:
- Slows extracellular calcium ion influx across myocardial cell membranes
- Slows conduction through the sinoatrial node and the atrioventricular node
- Slows the ventricular conduction rate in atrial fibrillation and atrial flutter
Indications:
- Atrial fibrillation with rapid ventricular rate
- Atrial flutter with rapid ventricular rate
- Supraventricular tachycardia