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SCRIPT: Pharmacology > Dosing and calculation > Flashcards

Dosing and calculation Flashcards

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3
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What unotes should doses be written for paediatrics (& all?)

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Mg unless otherwise specified in the BNF

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4
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How do you calculate lean body weight? [1]

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Body fat weight - actual body weight

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5
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In paedatriac intermediate life support, how should you calculate babys weight? [1]

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(Age + 4) x 2 (kg)

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6
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what does ‘%w/w’ mean? [1]

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7
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what does ‘%v/v’ mean? [1]

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7
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Explain what ‘%w/v’ means? [1]

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10
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Calculate how much sodium bicarbonate is in the following preparation:

’ Sodium bicarbonate 8.4% w/v 100ml’

A

An 8.4% solution contrains 8.4g in 100ml

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11
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How much MgS is in:

‘Magnesium sulfate 20% w/v 20ml ampoule for injection’

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12
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Explain how ratios can be used to express drug calculations [2].

A

1:1000 = 1g in 1000ml
- 1g in 1000ml = 1000mg in 1000ml = 1mg in 1ml

1:10 000 = 1 g in 10 000ml
- 1g in 10,000ml = 1000mg in 10,000ml = 1mg in 10ml = 100microgram in 1ml

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18
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In the BNF:
‘Child 3–5 months: 60 mg every 4–6 hours; maximum 4 doses per day”

Therefore max dose: 60x4 = 240mg

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What is the standard practise when withdrawing benzodiazepine medication?

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Change benzo to equivalent dose of diazepam then carefull reduce the dose of this to zero

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He takes 40mg twice a day morphine sulfate. He also takes 20mg morphine sulfate daily PRN.

Covert his 24hr dose of morphine sulfate to a fentanyl patch

Fentanyl 25 micrograms/ hr patch
Fentanyl 37 micrograms/ hr patch
Fentanyl 50 micrograms/ hr patch
Fentanyl 100 micrograms/ hr patch

A

He takes 40mg twice a day morphine sulfate. He also takes 20mg morphine sulfate daily PRN.

Covert his 24hr dose of morphine sulfate to a fentanyl patch

Fentanyl 25 micrograms/ hr patch
Fentanyl 37 micrograms/ hr patch
Fentanyl 50 micrograms/ hr patch
Fentanyl 100 micrograms/ hr patch

29
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Convert his oral morphine sulfate to diamorphine via sub infusion

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30
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What should vancomycin be diluted to a concentration of when dosing? [1]
What should the infusion rate not exceed? [1]

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5mg/ml
Should not exceed 10mg/minutes

31
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You need to prescribe 1 gram of vancomycin.

Describe how you decide what size infusion bag you would use [1]

NB: Vancomycin is infused at 5mg/ml

A

1 g = 1000 mg
Need to dilute to 5mg/ml
Therefore 1000 mg in 1000 ml = 1mg/ml
But we want 5mg/ml so divide 1000ml by 5 = 200ml
BUT bags only come in 250ml

32
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State how you would prescribe the correct infusion rate for vancomycin

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33
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What are the steps need to enact when prescribing NAC infusion? [4]

A
  1. Find out actual body weight: max weight should use is 110kg
  2. Add with glucose 5%
  3. The total dose regimen is to be prescribed and adminstered in three parts:
    - First (loading) dose is given over 1hr in 200ml of glucose 5%
    - Second dose given over the next 4hrs, in 500ml of glucose 5%
    - The third and final is given over 16hrs, 1 litre of glucose 5%
  4. Those dose of NAC varies at each steps:
    - For the first you need 150 mg/kg
    - For the second you need 50 mg/kh
    - For the third you need 100 mg / kg
    - Thats a total dose of 300 mg/kg over 21 hrs!

Look Up in BNF: Poisoning, emergency treatment

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Look up BNF xx

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How do you calculate volume required of a paraenteral drug? [1]

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Vol = (Dose prescribed x vol of solution) / amount of drug in solution

(same as vol required = what you want / waht youve got) x whats in it

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SCRIPT: Pharmacology (11 decks)

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