Don't do drugs (Drug Reactions)

Question 1

Coronary vasospasm

Answer 1

Cocaine

Sumatriptan

Question 2

Cutaneous flushing

Answer 2

Vancomycin
Adenosine
Niacin
Ca2+ channel blockers

Question 3

Dilated cardiomyopathy

Answer 3

Doxorubicin (adriamycin)

Daunorubicin

Question 4

Torsades de pointes

Answer 4

Class III (sotalol) & class IA (quinidine) antiarrhythmics

Question 5

Agranulocytosis

Answer 5

Clozipine
Carbamazepine
Cochicine
Propylthiouracil
Methimazole
Dapsone

Question 6

Aplastic anemia

Answer 6

Chloramphenicol
Benzene
NSAIDs
Propylthiouracil
Methimazole

Question 7

Direct Coombs-positive hemolytic anemia

Answer 7

Methyldopa

Question 8

Gray baby syndrome

Answer 8

Chloramphenicol

Question 9

Hemolysis in G6PD deficient patients

Answer 9

Isoniazid
Sulfonamides
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin

IS PAIN

Question 10

Megaloblastic anemia

Answer 10

Phenytoin
Methotrexate
Sulfa drugs

Question 11

Thrombotic complications

Answer 11

OCPs

Question 12

Cough

Answer 12

ACE inhibitors

Question 13

Pulmonary fibrosis

Answer 13

Bleomycin
Amiodarone
Busulfan

Question 14

Acute cholestatic hepatitis

Answer 14

Macrolides

Question 15

Focal to massive hepatic necrosis

Answer 15

Halothane
Acetaminophen
Valproic acid
Amanita phalloides

Question 16

Hepatitis

Answer 16

Isoniazid

Question 17

Pseudomembranous colitis

Answer 17

Clindamycin, ampicillin

Question 18

Adrenocortical insufficiency

Answer 18

Glucocorticoid withdrawal (HPA suppression)

Question 19

Gynecomastia

Answer 19

Spironolactone
Digitalis
Cimetidine
chronic Alcohol use
Ketoconazole
Estrogens

Some Drugs Create Awesome Knockers, Eh?

Question 20

Hot flashes

Answer 20

Tamoxifen

Clomiphene

Question 21

Hypothyroidism

Answer 21

Lithium
Amiodarone
Sulfonamides

Question 22

Hyperglycemia

Answer 22

Niacin
Tacrolimus
Protease inhibitors

Question 23

Fat redistribution

Answer 23

Glucocorticoids

Protease inhibitors

Question 24

Gingival hyperplasia

Answer 24

Phenytoin

Verapamil

Question 25

Gout

Answer 25

``` Furosemide Thiazides Niacin Cyclosporine Pyrazinamide ```

Question 26

Myopathies

Answer 26

``` Fibrates Niacin Colchicine Hydroxychlorquine Interferon alpha Penicillamine Statins Glucocorticoids ```

Question 27

Osteoporosis

Answer 27

Corticosteroids | Heparin

Question 28

Photosensitivity

Answer 28

Sulfonamids Amiodarone Tetracycline

Question 29

Rash (Stevens-Johnson Syndrome)

Answer 29

``` Penicillin Ethosuximide Carbamazepine Sulfa drugs Lamotrigine Allopurinol Phenytoin Phenobarbital ```

Question 30

SLE-like syndrome

Answer 30

Hydralazine Isoniazid Procainamide Phenytoin

Question 31

Tendonitis, tendon rupture, cartilage damage

Answer 31

Fluoroquinolones

Question 32

Diabetes insipidus

Answer 32

Lithium | Demeocycline

Question 33

Fanconi's syndrome

Answer 33

Expired tetracycline

Question 34

Interstitial nephritis

Answer 34

Methicillin NSAIDs Furosemide

Question 35

Hemorrhagic cystitis

Answer 35

Cyclophosphamide | Ifosfamide (prevent by coadminitering w/ mesna)

Question 36

SIADH

Answer 36

Carbamazepine | Cyclophosphamide

Question 37

Cinchonism

Answer 37

Quinidine | Quinine

Question 38

Parkinson-like syndrome

Answer 38

Antipsychotics Reserpine Metoclopramide

Question 39

Seizures

Answer 39

Bupropion Imipenem/Cilastatin Isoniazid

Question 40

Tardive dyskinesia

Answer 40

Antipsychotics

Question 41

Antimuscarinic

Answer 41

``` Atropine TCAs H1 blockers Neuroleptics Digoxin ```

Question 42

Disulfiram-like reaction

Answer 42

Flushing, N/V, SOB, circulatory collapse Metronidazole Some cephalosporins Procarbazine 1st gen sulfonylureas

Question 43

Nephrotoxicity/ ototoxicity

Answer 43

Aminoglycosides Vancomycin Loop diuretics Cisplatin