DNA Virus

Question 1

Foreign double stranded DNA fragments in neuron body

Answer 1

Herpes simplex virus

Question 2

what is the only DNA virus that is not double stranded?

Answer 2

Parvoviridae

Question 3

Which DNA virus is not an icosahedral

Answer 3

Pox

Question 4

What DNA viruses are naked?

Answer 4

think: PAPP
1) Papillomaviurs
2) Adenovirus
3) Parvovirus
4) Polyomovirus

Question 5

What are the DNA viruses?

Answer 5

think: HHAPPPy
1) Hepadna
2) Herpes
3) Adeno
4) Parvo
5) Pox
6) Papilloma

Question 6

What DNA viruses are circular?

Answer 6

1) Papilloma

2) Hepadna

Question 7

What does HSV-1 cause? HSV-2

Answer 7

1) Oral lesions, temporal lobe encephalatis

2) Genital lesions

Question 8

Viral cause of temporal lobe encephalitis

Answer 8

HSV-1

Question 9

What are the different Herpesvirues?

Answer 9

1) HSV 1 & 2
2) Varicella zoster
3) EBV
4) CMV
5) HHV-8

Question 10

Hepadna viruses

Answer 10

HBV

Question 11

Non-enveloped DNA virus that causes conjunctivitis, pneumonia, and febrile pharyngitis

Answer 11

Adenovirus

Question 12

What virus causes aplastic crises in Sickle cell pt.

Answer 12

Parvo B19

Question 13

Cause of fifths disease

Answer 13

Parvo B19

Question 14

Cause of progressive multifocal leukoencephalopathy

Answer 14

JC virus (polyomavirus)

Question 15

Cause of infectious mononucleosis, Burkitt’s/Hodgkin’s lymphoma

Answer 15

EBV

Question 16

Cause of mononucleosis with negative monospot test, pneumonia, retintis

Answer 16

CMV

Question 17

Owl’s eye inclusion

Answer 17

CMV

Question 18

Infected cells have intranuclear Cowdry A inclusions. Indicates what virus?

Answer 18

HSV

Question 19

Positive Monospot test indicates

Answer 19

EBV

Question 20

What viruses are found in the Hepadna class

Answer 20

1) HBV

Question 21

Hairy leukoplakia

Answer 21

EBV

Question 22

Squamous cell carcinoma

Answer 22

HPV

Question 23

Condylomata acuminata?

Condylomata lata

Answer 23

1) HPV 6 and 11

2) Trepnoma pallidum

Question 24

How does EBV enter B lymphocytes?

Answer 24

1) The complement component of CD21

Question 25

What is EBV responsible for causing?

Answer 25

1) Infectious mononucleosis
2) Nasopharyngeal carcinoma
3) Burkitt’s lymphoma
4) Lymphomas (Large cell immunocompromised type)

Question 26

What does Parvovirus B19 bind to infect a cell?

Answer 26

P antigen on erthryocytes

Question 27

What test is used to determine EBV?

Answer 27

Monospot

1) Detects heterogenous group of IgM antibodies
2) + for heterophil antibodies

Question 28

What is the Papanicolaou smear used for?

Answer 28

Determination of the presence of HPV

Papanicolaou = pap

Question 29

5 yr old has fever, irritability and refusal to eat. Painful gingival ulcers, swollen gums, and cervical lymphadenopathy.

Answer 29

HSV-1

Question 30

Cause of self-limited pharyngoconjunctival fever (fever, pharyngitis, cough, nasal congestion, conjunctivitis, and enlarged cervical lymph nodes)

Answer 30

Adenovirus

Question 31

How can parvovirus B19 present in children? Adults?

Answer 31

1) Fifths disease (erythema infectiosum, aplastic anemia

2) Arthritis involving the PIP metacarpal, knee and ankle joints; resolves spontaneously

Question 32

What are histological findings of an infection with hepatitis B

Answer 32

1) Hepatocytes show balooning degeneration, hepatocyte necrosis, and portal inflammation.
2) Hepatocellular cytoplasm becomes filled with spheres an has a g`ranular appearance

Question 33

How do the herpes viruses gain there envelope in comparison to other viruses?

Answer 33

1) Herpes viruses bud through and acquire the lipid bilayer envelope by budding through the nuclear membrane
2) Most bud through the plasma membrane of the host cell

Question 34

Most common cause of hemorrhagic cystitis in males

Answer 34

Adenovirus

Question 35

What dsDNA viruses have partial circular structure?

Answer 35

1) Hepadnavirus (HBV)
2) Papillomavirus
3) Polyomavirus (JC virus)