DNA Structure And Genome Composition Flashcards

1
Q

What is the central dogma?

A

The flow of genetic information from DNA to RNA to proteins

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2
Q

DNA to RNA is a process called

A

Transcription

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3
Q

RNA to protein is a process called

A

Translation

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4
Q

The building blocks of DNA and RNA are

A

Nucleic acids

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5
Q

A nucleotide consist of a _____ , _____ , _____. A nucleoside consists of a _____ and _____.

A

Phosphate, sugar (deoxyribose), and base

Sugar and base

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6
Q

The purine bases are ____ and ______
The Pyrimidines are ____ and ______

A

Adenine and guanine

Cytosine and thymine

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7
Q

The sugar in RNA is ____
The four bases in RNA are ____ , ____, ____, ____.

A

Ribose

Adenine guanine cytosine and Uracil

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8
Q

Nucleotides are joined by _____ bonds.
A free nucleotide will bind at its _____ carbon to another nucleotide at its _____ carbon. Nucleotides are added to the _____ _____ of a DNA strand.

A

Phosphodiester
5’ (5 prime)
3’ (3 prime
3’ terminus

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9
Q

______ is double stranded. ____ is single-stranded.

A

DNA
RNA

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10
Q

Two DNA strands are attached together via _____ bonds between bases. Adenine hydrogen bonds to ____. Guanine hydrogen bonds to ____.

A

Hydrogen
Thymine
Cytosine

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11
Q

It takes more energy to pull the ____ pair apart due to three hydrogen bonds, compared to only two hydrogen bonds in the ____ pair.

A

GC
AT

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12
Q

The sugar phosphate backbone is on the _____ of the alpha helix.

A

Outside

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13
Q

The human genome is ______ divided into _____ linear molecules.

A

3,200,000,000
24

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14
Q

Of the 24 chromosomes 22 are called _____ and two are called ____ chromosomes. Humans are ____, meaning, each cell has two copies of every chromosome.

A

Autosomes
Sex
Diploid

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15
Q

A _____ is a segment of DNA that is involved in producing a polypeptide chain (protein).

A

Gene

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16
Q

Only _____ percent of our genome encodes for proteins.

A

One

17
Q

____ ____ are short sequences in our DNA that are repeated, they tend to be enriched in certain regions of the chromosome.
Ex: TTAGGG is repeated in the _____ region

A

Tandem repeats
Telomeric

18
Q

_____ originated from normal genes but have mutated overtime. They may play a role in regulating the expression of regular genes

A

Pseudogenes

19
Q

Another genome in humans is found in the _____.

A

Mitochondria

20
Q

_____ ____ is becoming useful to treat and cure diseases

A

Genome engineering

21
Q

True or false
The central dogma of molecular biology posits that the flow of genetic information flows unidirectionally from DNA to proteins, as well as RNA directly to protein

A

False

22
Q

True or false
The complexity of an organism is not defined by its genome size or the number of genes

A

True
Amoebas genome is actually larger than the human genome

23
Q

True or false
Our genome is composed of many different genetic elements with the majority of it composed of coding protein sequences

A

False

24
Q

True or false
A gene is a unit of heredity, containing only the protein coding sequence

A

False
A gene contains both protein and non-protein, coding sequences, including promoter sequences and introns