Dna Replication Flashcards
1
Q
DNA helicase
A
Unwinds and separates the double stranded DNA creating 2 single strands
2
Q
Single strand binding proteins (SSBs)
A
Bind to the separated DNA strands to prevent them from reannelaing or forming secondary structures
3
Q
Primase
A
Synthesizes short RNA primers in the DNA template providing a starting point for DNA synthesis
4
Q
DNA polymerase
A
Enzymes that synthesize new DNA strands by adding nucleotides to the RNA primers
5
Q
Sliding clamp
A
Holds the DNA polymerase in place on the DNA strand
6
Q
Topoisomerase (gyrase)
A
Relieves the tension and supercoiling that occur ahead of the replication fork as the DNA unwinds
7
Q
Ligase
A
Joins okazaki fragments on the lagging strand by forming Phosphodiester bonds
