11.2

Question 1

Conservative model

Answer 1

Both strands of parent molecule remain intact

Question 2

Semiconservative model

Answer 2

One strand of parent molecule remains intact

Question 3

Dispersive model

Answer 3

Parts of parental molecule are dispersed throughout

Question 4

DNA replication requires

Answer 4

1. Something to copy : parental DNA molecule
2. Something to do the copying: enzymes (DNA polymerase)
3. Building blocks to make the copy: nucleoside triphosphates

Question 5

DNA replication occurs in 3 stages

Answer 5

1. Initiation: the process of replication starts
2. Elongation: new DNA strands are synthesized
3. Termination: the process of replication ends

Question 6

DNA polymerase

Answer 6

-matches template bases with complementary nucleotides and link incoming nucleotide to daughter strand

1. Add new bases to 3’ end of existing strands
2. Synthesize in 5’ to 3’ direction
3. Require a primer of RNA

Question 7

RNA polymerase vs DNA polymerase

Answer 7

RNA makes primer

DNA Extends primer

Question 8

Prokaryotic replication

Answer 8

1.Begins at one origin of replication
2. Is catalyzed by replisomes
3. Proceeds in both directions around the chromosome

Question 9

E. Colin has multiple DNA polymerase

Answer 9

DNA poly 1- replaces RNA primers with DNA
DNA poly 2- includes in DNA repair processes
DNA poly 3- main replication enzyme
All synthesize DNA in 5’ to 3’
All have 3’ to 5’ exonuclease activity (proof reading)

Question 10

Replication is semi-discountinuous

Answer 10

-DNA is composed of 2 anti parallel strands
-DNA polymerase can only synthesize in 5’ to 3’ direction