DNA replication Flashcards

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1
Q

zygote with an extra chromosome is called

A

trisomic

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2
Q

zygote that is missing a chromosome is called

A

monosomic

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3
Q

aneuploidy

A

a gamete with an abnormal chromosome number used in fertillization

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4
Q

polyploidy

A

more than 2 complete sets of chromosomes are present (triploidy 3 sets or tetreploidy 4 sets)

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5
Q

what are the 4 types of errors that can occur in meiotic division?

A

deletion (genes are missing), duplication (duplicated fragment reattaches), inversion (broken fragment reattaches backwards) , translocation (broken fragment attaches to a non-homologous chromosome)

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6
Q

helicase

A

enzyme that untwists and seprates the two strands of DNA at the replication fork.

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7
Q

single stranded binding protein

A

binds to seperated strands to stop them from reattaching

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8
Q

topoisomerase

A

swivels and rejoins the DNA strand upsteam of where it is being twisted

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9
Q

rna primer is synthesized by

A

primase

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10
Q

DNA polymerase

A

catalyzes the addition of the new DNA strand by adding ncleotides one by one (DNA polymerase 1 and 3 are most important)

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11
Q

what happens when a DNA strand is assembled 3’to 5’?

A

the strand is lagging, it is synthesized discontinuosly forming small fragments okazaki fragments, DNA ligase then fills in the gaps between the fragments according to DNA template.

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12
Q

plasmid

A

smaller circular DNA in addition to the larger circular DNA found in prokaryotes

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13
Q

heterochromatin

A

half wound chromatin structure

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