Cell cycle regulation Flashcards
In which phases do checkpoints occur?
G1, S and G2 (G1 is most important)
Do cells remain in G0 for life ?
No they can be removed based on external cues
What are protein kinases?
Proteins that are always present in the cell but require cyclin in order to become active they serve to active and deactivate proteins via phospharylation (important in G1 or G2 to signal go)
When does cyclin increase?
G2
what does separase do?
cleves cohesions between sister chromatids
lack of what will stop cell division?
essential nutients
what is density dependant inhibition and anchorage dependence?
density dependent inhibition is an external factor that will stop cell division, cells are to close together and will stop dividing. anchorage dependance is another external factor stating that cells must have a solid support attached in order to begin dividing.