DNA Genes and chromosomes Flashcards
DNA in prokaryotes
all types
single circular DNA molecule can be referred to as a nucleoid
plasmids are very small circular DNA
only containing a few genes
histones in prokaryotes
DNA in prokaryotic cells have noc histones
what are chromosomes made from
one long condensed DNA molecule associated with histones
purpose of histones
organise and condense DNA tightly so that it fits in the nucleus
what seals the ends of chromatids
protective structures called telomeres
Dna in mitochondria and chloroplast name
mtDNA
cpDNA
what is DNA in mitochondria and chloroplasts like
short circular
associated with no proteins
found in matrix and stroma
gene definition
base sequence of DNA that codes for the amino acid sequence of a polypeptide
function of mRNA
base sequences on mRNA molecules are ised by ribosomes to form polypeptide chains
function of tRNA
amino acids are carried to the ribosome by transfer RNA molecules
rRNA function
ribosomal RNA molecules form part of the structure of ribosomes
what determines the shape and behaviour of the protein
the shape and sequence of amino acids (primary structure)
this means that genes in DNA controls protein structure
do chromosomes contain lots of genes each
yes
position of a gene
locus
name for the different forms of genes that can exist
alleles
difference between alleles and original gene
slightly different nucleotide sequences but still occupy same locus on the chromosome
what is the DNA nucleotide base code
three letter code (codon) which codes for one amino acid per codon
how to know where individual genes start and stop
some codons code for start and end
importance of the start and stop codon
ensures that the cell reads the DNA correctly and produces the correct sequences of amino acids
what are degenerate codons
there are 4 bases so 64 different triplets available however only 20 occur in proteins
this means that many codons code for the same amino acid which means this code is degenerate
what is meant by a universal code
almost every organism uses the same triplet code = same amino acid
what is non coding DNA
DNA that doesnt code for any amino acids
where does non coding DNA occur
between genes as many base sequences will be repeated
can also be found in introns in genes
what happens to introns just before the m,RNA leaves the nucleus
non coding introns are removed and the coding sections are joined together in splicing
where is most non coding DNA in eukaryotic dna
introns which repeat throughout gene
state where telomeres are found within a chromosome as well as their function
end of chromosome
protect DNA from damage
Dna replication proccess
DNa is unzipped by DNA helicase - breaking hydrogen bonds
DNA polymerase adds free floating nucleotides to each unzipped strand
DNA polymerase can only work in the 3 to 5 prime direction
which way can DNA polymerase only work
DNA polymerase can only work in the 3 to 5 prime direction