DNA and RNA structure and function Flashcards
DNA
Deoxyribonucleic acid
Stores genetic information
RNA
Ribonucleic acid
Carries genetic information from the DNA to ribosomes
Ribosome
Formed from rRNA and proteins
DNA & RNA
Polymers
Chains of nucleotides called polynucleotides
Nucleotide parts
Phosphate, nitrogenous base, pentose sugar
Ester bond between phosphate and pentose
Glycosidic bond between base and pentose
Components of DNA nucleotide
Pentose sugar
Phosphate
Organic group - ATCG
Components of RNA nucleotide
Ribose
Phosphate
Organic group - AUCG
Difference between DNA and RNA nucleotide
DNA has deoxyribose, RNA has ribose
DNA has thymine, RNA has uracil
2 nucleotides
Link together by a condensation reactions with a phosphodiester bond linking them
Many nucleotides
Link together by many condensation reactions with many phosphodiester bonds liking them in a sugar-phosphate backbone.
DNA molecule
Double helix with 2 polynucleotide chains held together by hydrogen bonds between specific complementary base pairs
Anti-parallel
Triplet
Sequence of 3 bases in the DNA
Each triplet codes for a particular amino acid
Any changes to the triplet (gene mutations) can lead to different amino acids appearing in the polypeptide chain and can result in non-functional proteins/enzymes
Structure of RNA
Short polypeptide chain
Single-stranded
rRNA
Found in a ribosome along with protein
mRNA produced
Produced by transcription in the nucleus and then moves to the cytoplasm where it takes part in translation
tRNA
Involved in the process of translation
Structure of mRNA
Copy of a single gene in the DNA - has complementary bases and is single-stranded, straight chain
Relatively unstable molecule as it has no hydrogen bonds in its structure
Why is the actual number of amino acids likely to be less
Introns (non-coding) & stop codons
Codon
Sequence of 3 bases in the mRNA
Role of mRNA in protein synthesis
Copy of genetic info in DNA of 1 gene so is small enough to pass through nuclear pores into the cytoplasm
Structure of tRNA
Single stranded but they coil up to a clover-leaf shape that is held together by hydrogen bonds, making it more stable
2 important regions - amino acid binding site that picks up specific amino acids and an anticodon at other end that is complementary to codon
Relationship between codons and anticodons
Complementary
Relationship between anticodons and triplets
Same except DNA has thymine, RNA has uracil
Bond between amino acids
Peptide
TRNA involved
In process of translation
Carry particular amino acid to the ribosome to be added to the growing peptide chain
Explain how tRNAs are specific to particular amino acid
Matches with anticodons
DNA summary
Deoxyribose sugar, ATCG, 2 strands
V long, hydrogen bonds, double-helix
Triplets, v stable lifespan, site of action is nucleus
mRNA summary
Ribose sugar, AUCG, 1 strand
V short, no hydrogen bonds, single-stranded
Codon, v unstable lifespan, site of action is nucleus & cytoplasm
tRNA summary
Ribosome sugar, AUCG, 1 strand, v short
Hydrogen bonds, clover-leaf shape, anticodon
Some stability in lifespan, site of action is cytoplasm