DNA

Question 1

what is the structure of DNA like

Answer 1

double helix formed by condensation polymers

Question 2

what is the identity of the anti-cancer drug

Answer 2

cis platin

Question 3

how does cis platin work

Answer 3

binds with guanine and inhibits DNA replication

N of guanine has lone pairs which will form coordinate bonds with the Pt and the chloride ions are displaced by water. the water ligands are then displaced by Non guanine because it is a better ligand

Question 4

why would trans platin not work

Answer 4

because there is only one chlorine do bind with guanine

Question 5

what does it mean when enzymes are said to be stereospecific

Answer 5

that the active of the enzyme is so specific that it may only catalyse a reaction of one or the pair of enantiomers - which are stereoisomers - therefore the enzyme is streospeciifc

Question 6

describe a primary protein

Answer 6

sequence of amino acids

Question 7

describe a secondary protein

Answer 7

hydrogen bonds will further fold the sequnece of amino acids into beta pleated sheet and alpha helix

Question 8

describe a tertiary structure

Answer 8

unique 3d structure and is held by ionic, disulfide bridges and hydrogen bonding

Question 9

how can structures of primary proteins be found

Answer 9

the protein is refluxed with 6moldm-3 HCl to then undergo hydrolysis - it breaks the amide bonds between the amino acids and results in a mixture containing all the individual AA in the protein

Question 10

how many hydrogen bonds are between c and g

Answer 10

3

Question 11

how many hydrogen bonds are between a and t

Answer 11

2

Question 12

what can the active site be described as in relation to rate

Answer 12

the limiting factor

Question 13

when there are low concentration of substrate what can the order of reaction be described as

Answer 13

first