DM Flashcards
Type 1 DM Other Names
Insulin dependent DM
Brittle dx
Juvenile onset
Ketosis prone diabetes
Type 2 DM Other Names
Noninsulin dependent DM
Adult / Mature onset
Ketosis resistant DM
Stable DM
Receptor deficient DM
- Occurs because of beta cell destruction
- lead to insulinopenia / absolute insulin deficiency
- Will only manifest if _ of beta cells are destroyed
Type 1 DM
80-90%
Insulin resistance due to alteration or absence of insulin receptors
Type 2 DM
Occurs at any age group
Type 1 and Type 2
Most common to childhood / teens
Type 1 DM
Most common among adults
Type 2 DM
An Autoimmune Dx
(+) Autoantibodies
Type 1 DM
Pre-diabetes Stage Autoantibodies
Glutamic Acid Decarboxylase – adults
Insulin AubtoAb – common to children
Islet cells AutoAb
Tyrosine phosphatase (IA-2 and IA-2B)
Insulinoma-assoc. Protein 2-AutoAb
Zinc transporter 8 AutoAb
(+) Autoantibodies in adults
Glutamic Acid Decarboxylase
(+) Autoantibodies in common to children
Insulin AubtoAb
Type 2 Risk Factors
Genetics, Race, Ethnicity, Obesity, Sedentary Lifestyle, Dyslipidemia, Hypertension, Polycystic Ovarian Syndrome
Symptoms develop gradually
Milder symptoms / sometimes asymptomatic
Type 2 DM
Symptoms develop gradually
Milder symptoms / sometimes asymptomatic
Type 2 DM
Symptoms develop abruptly
Type 1 DM