DJD And Osteoarthtitis Flashcards
5 risk factors to consider for OA?
Age, female, obesity, trauma, and occupation
3 main patho ways causing problems in osteoarthritis?
Lose hyaline articular cartilage type 2 collagen
Synovial inflammation releasing IL1b and TNF
Weakness of muscles controlling the joint
8 common places for osteoarthritis?
Cervical spine Lumbar spine 1st CMC PIP DIP Hip Knee 1st MTP
What is important about laboratory studies with OA?
Normal
5 things to see on radiographs for OA?
Asymmetric joint - space narrowing Subchondral sclerosis - thickening Osteophytes Bone cysts Joint mice
What is the most common classification of OA and what joints are involved?
Primary
All of the 8 mentioned
What are 6 causes of secondary OA?
Trauma, joint infection, surgical repair, congenital joints, metabolic and endocrine
What are three examples of secondary OA and which joints do they go after?
Hemochromatosis - iron overload - 2/3 MCP joints and wrist
Pseudogout (CPPD) - MCP, wrist, knees, hips and shoulders
Hyperparathyroidism - wrist, MCP
What two joints are commonly affected by erosive OA, what gender, what is an identifying feature from OA, and what do we see on radiograph of it?
DIP and PIP
Female
More pain that OA in hands
Central erosions of the finger bones and “seagull” appearance in finger joints.
6 differentials for OA?
Pseudogout Gout Psoriatic arthritis Charcot joint RA Osteonecrosis
How do we characterize diffuse idiopathic skeletal hyperostosis?
Gender most commonly affected?
4 clinical signs?
Non inflammatory condition with calcification and ossification of spinal ligaments
Males
Back pain, stiffness, t spine, 4 continuous vertebral levels on the fight usually involved
3 meds for the treatment and management of OA?
NSAIDS
Topical capsaicin
Topical NSAIDS
2 other treatments for OA besides NSAIDS and non pharm methods?
Injections and surgery
