diuretics

Question 1

Proximal convoluted tubules

Answer 1

Carbonic anhydrase inhibitors: Acetazolamide

Question 2

All segments of nephron, except thick ascending loop of Henle

Answer 2

Osmotic diuretics: Mannitol, glycerol

Question 3

Thick ascending limb of loop of Henle

Answer 3

Loop diuretics/High-ceiling diuretics:
Furosemide/Frusemide, bumetanide, torsemide, ethacrynic acid

Question 4

Early (proximal) part of the distal tubule

Answer 4

• Thiazides: Hydrochlorothiazide, Chlorothiazide, benzthiazide
• Thiazide like diuretics: Chlorthalidone, metolazone,
  indapamide

Question 5

Late distal tubules and collecting duct

Answer 5

Potassium sparing diuretics

✓ Aldosterone antagonists: Spironolactone, eplerenone

✓ Direct inhibitors of sodium channels: Amiloride, triamterene