Diuretics Flashcards
1
Q
Name the 3 classes of diuretics
A
Loop diuretics, thiazide diuretics and potassium sparing diuretics.
2
Q
What is the MOA of loop diuretics?
A
Inhibits Na+/K+/2CI- cotransporter in the thick ascending loop of Henle
3
Q
What is the MOA of thiazide diuretics?
A
inhibits the sodium chloride transporter in the early distal convoluted tubule
3
Q
What is two adverse effects of diuretics?
A
hyperkalaemia and hypernatraemia
4
Q
What should you monitor with diuretics? (3)
A
Monitor serum electrolytes, potassium and renal function baseline.
5
Q
What is the difference in potency of loop and thiazide diuretics?
A
Loop- potent (20-25% of sodium is reabsorbed)
Thiazide- not potent (5-10% of sodium is reabsorbed)
