COPD Flashcards
What is the main inflammatory mediator of COPD?
- Neutrophils
What are the clinical characteristics of COPD?
- Late onset
- Occupational/environmental exposure
- Smoking
- Cough, sputum plugs and SOB
Which is the most effective intervention for COPD?
Smoking cessation
What are 4 risk factors of COPD?
Smoking, dust, fumes, indoor and outdoor pollutants.
What are the two conditions COPD encompasses?
Chronic Bronchitis, Enphysema
How COPD used to be referred to at times?
COLD – Chronic Obstructive Lung Disease / COAD – Chronic Obstructive Airways Disease
What technique should be offered to all COPD patients with functional impairment?
Pulmonary rehabilitation improves exercise capacity, dyspnoea, QoL, and reduces hospitalisation.
Explain the pathophysiology of COPD
A progressive lung condition characterised by airway inflammation that is not fully reversible.
Onset is > 45.
Name 4 diagnosis –relevant history in COPD.
Smoking History, Occupational exposure, presence or absence of other respiratory illness, Comorbidities
What is the rationale for drug use in COPD?
Symptom relief
improvement of exercise tolerance and QoL
prevention or treatment of exacerbations and complications of COPD.
What is the rationale for recommending to check immunisation status: pneumococcal and annual influenza vaccines in COPD?
Influenza vaccination decreases the risk of exacerbations due to influenza strains; pneumococcal vaccination reduces the risk of exacerbations and of community-acquired pneumonia.
Name 4 clinical features differentiating COPD & Asthma.
Smoking – nearly all in COPD, possibly in Asthma
Symptoms under age 35 – rare in COPD, common in Asthma
Chronic Productive cough – common in COPD, uncommon in Asthma
Breathlessness – persistent and progressive in COPD, Variable in Asthma
What is the primary cause of COPD?
COPD is primarily caused by long-term exposure to irritating gases or particulate matter, most commonly from smoking.
What happens in the lungs during COPD?
In COPD, there is chronic inflammation and narrowing of the airways, leading to obstructed airflow. The alveoli lose their elasticity, making it difficult to exhale air.
How does COPD progress over time?
COPD typically progresses slowly.
The airway inflammation and lung damage worsen, leading to increasing breathlessness and decreased lung function.