Diuretica Flashcards

1
Q

acetazolamide

A

carboanhydraseremmer (proximale tubulus) -> minder H+ ionen die uitgewisseld kunnen worden met Na -> meer Na in lumen
- glaucoom
- pas op: metabole acidose

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2
Q

furosemide

A

lisdiuretica (dikke opstijgende lis Henle): inhibitie Na-K-2Cl symporter
- oedeem!
- hypertensie
- intoxicatie
- samen met osmotische diuretica bij ANI
Hond & kat

+ stimulatie prostaglandine vorming => vasodilatatie => urinaire productie stijgt

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3
Q

torasemide

A

lisdiuretica (dikke opstijgende lis Henle): inhibitie Na-K-2Cl symporter
- oedeem!
- hypertensie
- intoxicatie
- samen met osmotische diuretica bij ANI
ENKEL hond

+ stimulatie prostaglandine vorming => vasodilatatie => meer urinaire productie

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4
Q

chlorothiazide

A

thiazides (distale tubulus) -> inhibitie Na-Cl cotransporter
- chronische therapie hartinsufficiëntie
- calcium-oxalaat urolithen

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5
Q

hydrochlorothiazide

A

thiazide (distale tubulus) -> inhibitie Na-Cl cotransporter
- chronische therapie hartinsufficiëntie
- calcium-oxalaat urolithen

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6
Q

triamterene

A

kaliumsparende diuretica (ductus colligens) -> blokkeren Na kanalen
- beperkte indicaties
- ascites

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7
Q

amiloride

A

kaliumsparende diuretica (ductus colligens) -> blokkeren Na kanalen
- beperkte indicaties
- ascites

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8
Q

spironolactone

A

kaliumsparende diuretica (ductus colligens) -> blokkeren aldosteron receptor
- beperkte indicaties
- ascites

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9
Q

mannitol

A

osmotische diuretica ==> aantrekken vocht
- intoxicatie
- acute nierfalen
- hersenoedeem
NIET bij oedeem door hartinsufficiëntie

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10
Q

desmopressine

A

anti-diuretica: binding vasopressine 2 R
- toepassing: centrale diabetes insipidus

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11
Q

glycerol

A

osmostische diuretica ==> aantrekken vocht
- intoxicatie
- acute nierfalen
- hersenoedeem
NOOIT bij hartinsufficiëntie

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