Immunomodulatie Flashcards

1
Q

oclacitinib

A

JAK1 inhibitor -> geen JAK/STAT
- atopische dermatitis hond

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2
Q

lokivetmab

A

monoklonaal antilichaam tegen IL-31 -> geen JAK/STAT
- atopische dermatitis hond

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3
Q

cyclosporine

A

inhibitie T-cel activatie door inhibitie IL-2
- atopische dermatitis hond en kat

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4
Q

prednisone

A

immunosuppressie + anti-inflammatoir door binding intracellulaire receptoren -> translocatie naar nucleus -> binding responsieve genen
- 1e keus behandeling immuungemedieerde aandoening (bv. atopische dermatitis)

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