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1
Q

streptomycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S fout AZ

2 - // - 5 - //

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2
Q

dihydrostreptomycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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3
Q

neomycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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4
Q

gentamicine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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5
Q

amikacine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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6
Q

tobramycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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7
Q

kanamycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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8
Q

paromomycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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9
Q

apramycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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10
Q

spectinomycine

A

aminocyclitols (enige: spectinomycine) -> 30S

2 - // - 5 - //

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11
Q

colistine

A

polymyxines (verdringen tweewaardige ionen thv fosfolipiden)

// - // - 5 - 2
gram+ zijn resistent

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12
Q

chloramfenicol

A

fenicolen (chloramfenicol, thiamfenicol, florfenicol) -> 50S

5 - 5 - 3 - 5

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13
Q

thiamfenicol

A

fenicolen (chlorfenicol, thiamfenicol, florfenicol) -> 50S

5 - 5 - 3 - 5

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14
Q

florfenicol

A

fenicolen (chlorfenicol, thiamfenicol, florfenicol) -> 50S

5 - 5 - 3 - 5

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15
Q

tetracycline

A

tetracyclines 1 (tetracycline, oxytetracycline, chlortetracycline) -> 30S

2 - 2 - 2 - 2

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16
Q

oxytetracycline

A

tetracyclines 1 (tetracycline, oxytetracycline, chlortetracycline) -> 30S

2 - 2 - 2 - 2

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17
Q

chlortetracycline

A

tetracyclines 1 (tetracycline, oxytetracycline, chlortetracyline) -> 30S

2 - 2 - 2 - 2

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18
Q

doxycycline

A

tetracyclines 2 (enkel doxycycline) -> 30S

4-4-4-4

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19
Q

sulfasalazine

A

sulfonamiden -> competitie PABA voor dehydropteroaat synthetase enzym -> inhibitie foliumzuur

2 - 2 - 2 - 2

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20
Q

sulfadiazine

A

sulfonamiden (competitie met PABA voor dihydropteroaat synthetase enzym -> inhibitie foliumzuur)

2- 2 - 2 -2

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21
Q

sulfachlorpyrazine

A

sulfonamiden (competitie met PABA voor dihydropteroaat synthetase enzym -> inhibitie foliumzuur)

2 - 2 - 2 - 2

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22
Q

sulfamethoxazole

A

sulfonamiden (competitie met PABA voor dihydropteroaat synthetase enzym -> inhibitie foliumzuur)

2 - 2 - 2 - 2

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23
Q

trimethoprim

A

diaminopyrimidines (inhibitie dihydrofolaat reductase enzyme -> geen DNA synthese)

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24
Q

nitrofurantoine

A

nitrofuranen -> remming Krebs enzymen

25
Q

nalidixinezuur

A

fluoroquinolonen 1 (nalidixinezuur, flumequine) -> inhibitie DNA gyrase en topoisomerase IV

// - // - 3 - //

26
Q

flumequine

A

fluoroquinolonen 1 (nalidixinezuur, flumequine) -> inhibitie DNA gyrase en topoisomerase IV

// - // - 3 - //

27
Q

marbofloxacine

A

fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV

2 - // - 5 - //

28
Q

danofloxacine

A

fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV

2 - // - 5 - //

29
Q

danofloxacine

A

fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV

2 - // - 5 - //

30
Q

enrofloxacine

A

fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV

2 - // - 5 - //

31
Q

orbifloxacine

A

fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV

2 - // - 5 - //

32
Q

pradofloxacine

A

fluoroquinolonen 3 (enkel pradofloxacine) -> inhibitie DNA gyrase + DNA topoisomerase IV

5 - 2 - 5 - 2

33
Q

cloxacilline

A

penicillines (resistent) -> inhibitie transpeptidatie -> disruptie celmembraan

staph/strep - // - // - //

34
Q

ampicilline

A

penicillines (breed spectrum: ampicilline, pivampicilline, amoxicilline) -> inhibitie transpeptidatie -> disruptie celmembraan

4 - 4 - 4 - 4

35
Q

pivampicilline

A

penicillines (breed spectrum: ampicilline, pivampicilline, amoxicilline) -> inhibitie transpeptidatie -> disruptie celmembraan

4 - 4 - 4 - 4

36
Q

amoxicilline

A

penicillines (breed spectrum: ampicilline, pivampicilline, amoxicilline) -> inhibitie transpeptidatie -> disruptie celmembraan

4 - 4 - 4 - 4

37
Q

cefazoline

A

cephalosporines 1 (cefazoline, cefapirin, cefalexine) -> inhibitie transpeptidatie -> disruptie membraan

5 - 5 - 2 - 5

38
Q

cefapirin

A

cephalosporines 1 (cefazoline, cefapirin, cefalexine) -> inhibitie transpeptidatie -> disruptie membraan

5- 5 - 2 - 5

39
Q

cefalexine

A

cephalosporines 1 (cefazoline, cefapirin, cefalexine) -> inhibitie transpeptidatie -> disruptie membraan

5 - 5 - 2 - 5

40
Q

ceftiofur

A

cephalosporines 3 (ceftiofur, cefovecin, cefoperazone) -> inhibitie transpeptidatie -> disruptie membraan

4 - 4 - 4 - 4

41
Q

cefovecin

A

cephalosporines 3 (ceftiofur, cefovecin, cefoperazone) -> inhibitie transpeptidatie -> disruptie membraan

4 - 4 - 4 - 4

42
Q

cefoperazone

A

cephalosporines 3 (ceftiofur, cefovecin, cefoperazone) -> inhibitie transpeptidatie -> disruptie membraan

4 - 4 - 4 - 4

43
Q

cefquinome

A

cephalosporines 4 (enige: cefquinome) -> inhibitie transpeptidatie -> disruptie membraan

4 - 4 - 4 - 4

44
Q

clavulaanzuur

A

beta-lactamase inhibitor -> geen antimicrobiële activiteit

45
Q

erythromycine

A

macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S

5 -5 - 2 - 5

46
Q

spiramycine

A

macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S

5 - 5 - 2 - 5

47
Q

tylosine

A

macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S

5 - 5 - 2 - 5

48
Q

acetylisovaleryltylosine

A

macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S

mycoplasma, R. equi, diarree bij oraal

5 - 5 - 2 - 5

49
Q

tilmicosine

A

macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S

5 - 5 - 2 - 5

50
Q

tulathromycine

A

macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S

5 - 5 - 2 - 5

51
Q

azithromycine

A

macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S

52
Q

clarithromycine

A

macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S

5 - 5 - 2 - 5

53
Q

lincomycine

A

lincosamiden (clindamycine, lincomycine, pirlimycine) -> 50S

5 - 3 - 2 - 3

54
Q

clindamycine

A

lincosamiden (clindamycine, lincomycine, pirlimycine) -> 50S

5 - 3 - 2 - 3

55
Q

pirlimycine

A

lincosamiden (clindamycine, lincomycine, pirlimycine) -> 50S

5 - 3 - 2 - 3

56
Q

tiamuline

A

pleuromutilins (samen met valnemuline) -> 50S

inhibeert CYP: hoge gehalte ionofore coccidiostatica!

4 - 4 - 2 - 4

57
Q

valnemuline

A

pleuromutilins (samen met tiamuline) -> 50S

4 - 4 - 2 - 4

58
Q

rifampicine

A

rifamycines -> inhibitie RNA polymerase nodig voor omzetting DNA naar RNA

R. equi, diarree paard

Farmaco (11 decks)

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