DIT other - Advanced Editor for pics Flashcards
BH4 (x2), Vit B6, Vit C - Epinephrine
Cofactors for E synth
Epinephrine synth path
Phenylalanine -> Tyrosine -> L-DOPA -> DA -> NE -> E P-hydroxylase, T-hydroxylase, DOPA decarboxylase, DA B-hydroxylase
NE Metabolism (2)
MAO, COMT DA -> HVA NE ->VMA E ->metanephrine
Gpr Coupled R - Major 3, paths, main receptor types found in each (mnuemonics)
Mneumonics: MAD 2’s, Cutsies HAVe 1 M&M
Vmax
Non-competitive Inhibitor
Zero order velocity
Max rate at which can undergo rxn (substrate bound to all enzymes)
[S] is proportional to Velocity
Non-competitive inhibitor will lower Vmax
(nothing to Km)
Km
Competitive Inhibitor
= [S] at 1/2 Vmax
decrease Km = Increase affinity of S for enzyme
Competitive inhibitor will increase Km
(nothing to Vmax)
Substrate concentration vs reaction velocity
Line-Weaver Burke Plot
IRV, TV, ERV, RV
IC, VC, FRC, TLC
Air volumes
Volume vs Static Pressure
chest wall vs lungs
Touch receptors (5)
Neural Crest Cells
Nissle Body
AA breakdown with PLA2
Brachial arches
COW angio
COW posterior angio
Parietal Cortex lesion
Hypothal nucleus anterior
Posterior hypothal lesion
poster = hyperthermia
mammilary body = wernikie-koffman (opthalmaplegia with ataxia)
Brain lesion rule of 4’s
Wallenberg syndrome
Hydrocephalus (4 types)
Layers for an LP
GBM pseudopalasading
Meningioma
Pilocytic astrocytoma
HISTO
Reticular fibers with eiosinophilic corkscrew
Meduloblastoma
HISTO
HWR around central fibrils
Ependymoma
HISTO
perivascular pseudo-perivascular
Lewy Body
Creutz-Fild Jacobs
HISTO
Looks like sponge
Dementia workup
Dementia Plus – other dz
Path to make Epi
V receptors
H Receptors
Gq, Gi, Gs pathway
Phase I reactions
Phase 2 reactions
Cardiac Embryology from just V and A
CoArc Rib finding CXR
CO vs RA Pressure graph
4 Shock types
Pressure-Volume Loop
A, P, C inc
Axis CV map
Bone Ds
Ewing sarcoma, 22;11
Bone Met - mnemonic
Osteo perosis
Osteopetrosis
Paget bone dz
Osteofibrosacystica
Bone Ds Labs
Hip Fx arteries
Pseduogout knee xray
SLE
SLE Nephritis - #1 death HISTO
Pemphigus Vulgaris
anti-desmosome imaging for Ab
Lichen Planus
HISTO
Melanoma
Male female Repro Development
Seminnoma - testicle
Yolk sac histo testicle
Choriocarcinoma histo
Leydig cell tumor testicle histo
HY Testicle Tumors
Prostate CA - periph zone histo
SCC of vulva - histo
CIN
normal menstural endometrial transitions - histo
Serous tumor
Ovarian epith tumors - mnemonic
Dysgerminoma - histo
Granulosa cell tumor - histo
Ovarian tumors
krukenberg tumor - histo
edward syndrome
Patau syndrome
Quad screen for trisomies
Gaucher dz - histo
macropahge with fibrils - looks like crumpled tissue paper
Niemman pick dz - histo
foam cells
Hurler syndrome
breast anatomy
Single breast lobule
Fibroadenoma
DCIS, LCIS - with histo
LCIS - histo with signet rings
MS
Neck anatomy - posterior triangle
Neck anatomy anterior triangle
A
A1
A2
A3
A4
A6
A5
A7
A8
A9
A10
A11
A12
A12
Touch receptors (5)
retinal detachment
1 salivary tumor - Pleomorphic adenoma
Hernias at LES -2
Splenic blood supply 1
Spleenic blood supply 2
Abdominal ligaments
Abd retroperitoneal - mnemonic
Adominal CT
Small bowel histo
Meckel Diverticulum scan
Achalasia - barium swallow finding
Chronic gastritis - histo
Menetrier dz
Schilling test - IF issue
Gastric CA (histo)- what has 50% chance underlying GI malignancy?
Ancanthosis nigricans
Whipple dz - histo
Bacterial overgrowth - histo
Meckel diverticulum “2s”
intususception - imaging
GI patho summary - ABCs of SBO
Pectinate line - superior
Pectinate line inferior
Adenomatous polyps - tubular histo
atypia of tubular glands
colon CA - barium
Crohn dz - histo and tx
Ulcerative colitis
Pancreatitis - mnemonic
liver duct anatomy
Cirrhosis - histo
Liver patho - summary
hemochromatosis
dying hepatocyte histo
Councilman bodies
Bili issues summary
PSC - with ERCP
Cholelithiasis - 4F’s
Cholangitis - triad and pentad
PBC vs PSC
Eqn to measure PaCO2
A-a gradient
PaO2 and FiO2
PE - EKG findings
Tension PTX - CXR
FEV1/FVC ratio - graphs
Asthma findings
Charcot Layden Crystal
COPD v Chronic Bronchitis v Emphysema
Measurement for chronic bronchitis
PTX - CXR
Emphysema - CXR and subtypes
Emphysema - CXR, including severe
Anti-neutrophil cytoplasmic (5)
Restrictive lung Dz
Asbestos and silicosis
Sarcoidosis - mnemonic
Ideopathic pulmonary fibrosis
Rx cause restrictive lung disease
4 Lung CA types - SCC histo
SCC - kerratin pearl
Summary Lung CA
Syndromes
Paraneoplastic+
Lobar typical PNA CXR
Diffuse patchy Atypical PNA
Lung abcsess CXR
Pleural effusion CXR
Transudate vs Exudate Pleural effusion
Cushing’s Reflex to cerebral ICP increase
Secondary HTN
Aortic dissection CT
Causes of HTN
Hormones impacting gastric acid
Drugs impacting gastric acid
Difference between: Arteriosclerosis, Arteriolosclerosis, Atherosclerosis
Atherosclerosis pathology
Normal heart vasculature
Nodal vacsulature
Most likely chest pain in situations
Pyloric stenosis
Major thalamic nuclei: VPL, LGN, VPM, Ventral anterior
MI ECG
Pulm HTN atery changes
Heart layers and patho ECG
ECG and corresponding heart areas
Post-MI Cx
MI Tx
HCM
HCM features and Tx
Restrictive CM - mnemonic
Dilated CM CXR
Infective Endocarditis
Roth Spots
Inf Endocarditis - mostly caused by
Culture negative Infective Endocarditis (bc all are intracellular)
SLE causes LSE - sterile vegitations on both sides of heart valve
4 causes of strep pyogenes
Erythema marginatum
Dx Acute Rhumatic Fever - Histo
Acute pancreatitis
Chronic constrictive pancreatitis
Cardiac tamponade - pulsus paradoxus - septum into LV during inspiration
Compare vs pericarditis
Pulsus paradoxus - anytime exaggerted breathing
causes:
cardiac tamponad - ECG
Tertiary syphilis
Most common primary tumor adult - LA myxoma
Primary cardiac tumor in children
rhabdomyoma
PBC vs PSC
Takayasu arteritis
Giant cell arteritis
Px: unilateral headache, jaw claudication, vision loss, elevated ESR
Look for temporal wasting and large temporal artery
giant cell arteritis Dx
Tx = high dose steroids
Kawasakis
T Obliteranes
Male smokers, 40 yo
PAN
Negative ANA rules out*
Henlock-Schonlein Purpura - IgA vasculitis
Eoi gran with polyangitis
Positive P-ANCA
P vs C-ANCA
GPA
Saddle nose deformity
GPA Histo - see vessel surrounded by giant cells/lymphocytes
C-ANCA positive
GPA Tx
Microscopic polyangitis - how rule out?
GPA is C-ANCA positive
Microscopy polyangiitis is P-ANCA positive
Vasculitis HY
Sturge-Weber Disease
=leptomeningeal angioma
with picture
Strawberry hemangioma
Hemangioma
Pyogenic granuloma
Cystic hygroma
Bacillary angiomatosis
Glomus tumor
Kaposi Sarcoma Types + image
Angiosarcoma
Lymphangiosarcoma
HY other vasculitities
HY Biostats equations
Infective Endocarditis organizsm
include HACEK - rare is answer