Disorders of Cognition Flashcards

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1
Q

Cool fact about long term memory?

A

Unlimited capacity (things can be lost or only recalled with a certain trigger but no limit on amount of memory you can store)

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2
Q

What is involved in retrieving memories? And what else does it do?

A

Hippocampus

-Also converts them from short to long term memories

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3
Q

How many types of memory and what are they?

A

3 types

  • Episodic
  • Semantic
  • Procedural
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4
Q

What is episodic memory?

A

Memory of experiences

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5
Q

What is semantic memory?

A

Memory of facts

-Don’t remember where you learnt facts just that you recall them

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6
Q

What is procedural memory?

A

Acquired memory through repeating tasks

- automatic

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7
Q

What is primary and recency effect?

A

Idea that when recalling items from a list we remember the start and the end best

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8
Q

What is delirium?

A

Acute deterioration in mental functioning arising over hours or days that is triggered mainly by acute medical illness, surgery, trauma or drugs

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9
Q

RF for delirium?

A
  • Increased age
  • Pre-existing cognitive impairment
  • Post-op
  • Sensory impairment
  • Prev episode of delirium
  • Drug/alcohol dependence
  • Depression
  • Polypharmacy
  • Multiple comorbids
  • ICU admission
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10
Q

Causes of delirium?

A

D: Drugs (benzos, narcotics, ACh)
E: Electrolyte disturbance (hyponatraemia)
L: Lack of drugs (withdrawal)
I: Infection (UTI, sepsis)
R: Reduced sensory input
I: Intracranial (stroke, subdural haemorrhage)
U: Urinary retention
M: Metabolic (AKI, hypoglycaemia, hypothyroid, B12, Ca)

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11
Q

Signs and symptoms of delirium?

A
  • Acute onset
  • Transient and fluctuating course of lucid intervals
  • Lasts days to months depending on underlying cause
  • Contrast to dementia which is slow and progressive
  • Altered consciousness
  • Inattention and impaired memory
  • Emotional disturbance
  • Sleep cycle reversed
  • Insomnia
  • Disturbing dreams and nightmares
  • Disorientation
  • Hallucinations and illusions
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12
Q

Types of delirium?

A

Hyperactive > agitated, aggressive, wandering, easy to diagnose
Hypoactive > withdrawn, apathetic, sleepy, coma, harder to diagnose but twice mortality rate

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13
Q

Screening for delirium?

A
  • All ptnts over 65 should be screened on admission
  • 4AT score
  • Confusion assessment method (CAM)
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14
Q

4AT score?

A

Alertness
AMT4 (age, DOB, place, year)
Attention
Acute change or fluctuating course

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15
Q

Management of delirium?

A

TREAT UNDERLYING CAUSES

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16
Q

Prescribe for delirium?

A
  • Standard antipsychotic (haloperidol)

- If someone has LBD/PD cant give haloperidol so give lorazepam

17
Q

What not to prescribe in delirium?

A

Sedating drugs can worsen it

18
Q

What can cause delirium?

A

Infection: CVS disorders
Intracranial/d=subdural haemorrhage, MI, PE, CF
Hypoxia: Endocrine disorders, diabetes complications
GI disorders: liver failure, pancreatitis
GU disorders: UTI, renal failure
Intoxication: Alcohol, drugs
Neurological disorders: Head injury, meningitis, encephalitis, tumours, epilepsy

19
Q

Investigation for delirium?

A
  • FBC, U&Es, LFTs
  • FORMAL cognitive tests
  • Urine analysis
  • Thyroid function tests
  • Blood glucose
  • CRP
  • B12 and folate
  • CXR
  • MRI/CT brain