Depressive Disorder Flashcards

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1
Q

What is depressive disorder?

A

Disorder where symptoms of unhappiness become qualitatively different and pervasive or interfere with normal functioning

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2
Q

Who gets depressive disorder?

A
  • More than 50% of cases before age 30

- Onset usually late 20s-30s

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3
Q

Criteria for depressive disorder?

A
  • Depressive episode should last at least 2 weeks
  • No hypomanic or manic episodes in individual’s life
  • At least 2 of the following symptoms:
    - Depressed mood
    - Loss of interest or pleasure
    - Decreased energy

+
Additional symptom or symptoms to make at least 4 (eg guilt, poor concentration etc)

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4
Q

Acronym to help assess depressive episode?

A

MEE

  • Mood
  • Energy
  • Enjoyment
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5
Q

Additional symptom list in depressive episodes?

A
  • Loss of confidence
  • Guilt
  • Suicidal ideas or behaviours
  • Poor concentration
  • Agitation/retardation
  • Sleep in disturbance
  • Changes in appetite
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6
Q

What is dysthymia?

A

Mild or moderate depressive illness that lasts intermittently for 2 years or more

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7
Q

What is psychotic depression?

A

Occurs in those with severe depression where thinking becomes psychotic

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8
Q

What usually occurs in psychotic depression?

A

Hallucinations within the theme of depression

-Voices telling them that they are a failure

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9
Q

What syndrome can occur in psychotic depression?

A

Cotard syndrome
-Nihilistic delusions can occur where it is believed by the patient that a part of them us dead or decomposed or annihilated or they don’t exist entirely as a human being

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10
Q

Mental state exam in depressive disorder?

A

Appearance: Slouching, tired, unkempt, dishevelled

Behaviour: Upset or teary

Speech: Slowed down speech, monotonal, low volume, poverty of speech

Mood: low

Affect: Blunted, flattened, not responding much

Thoughts: Suicidal thoughts/self harm, guilt, shame, thought blocking

Perception: Probably normal unless psychotic

Cognition: Poor concentration and memory, but most likely orientated

Insight: Generally aware of how they are feeling

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11
Q

Initial screening for depressive disorder?

A

2 screening questions: If answer to one or both is yes then person should be assessed for depressive illness

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12
Q

What are the 2 initial screening questions?

A
  • During the last month have they been feeling down, depressed or helpless
  • During the last month, have you been bothered by having little interest or pleasure in doing things
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13
Q

Other screening tools for depressive disorders?

A
  • PHQ-9 (patient health questionnaire)

- Hospital anxiety and depression scale

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14
Q

Possible physical causes of depression?

A
  • Thyroid disease
  • Cushing’s
  • Hyperparathyroidism
  • Corticosteroid treatment
  • Brain tumours
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15
Q

Management of depression patients who are actively suicidal?

A

Admission to hospital

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16
Q

Treatment for mild to moderate depression?

A

Talking therapies mainly CBT

17
Q

Treatment for moderate and severe episodes of depression?

A

Medication

1st line= SSRI

18
Q

What is a first line antidepressant and examples of it?

A

SSRI

  • Citalopram
  • Escitalopram
  • Fluoxetine
  • Paroxetine
  • Sertraline
19
Q

Which SSRI is best?

A

Little evidence to suggest one is best

  • Escitalopram is probably best all round but
  • Sertraline is also well established and has good cardiac safety
20
Q

How long does it usually take anti-depressants to work?

A

2-4 weeks

21
Q

Treatment for a first episode of depression?

A

-Antidepressant should be given for at least 6 months after full recovery without reducing the dose

22
Q

Treatment for second episode or more of depression?

A

Antidepressants should be continued for 1-2 years after full recovery without reducing the dose

23
Q

Treatment for life-threatening depressive illness particularly with psychotic symptoms?

A

Electroconvulsive therapy