Diseases Ass'd w/ Neoplasms

Question 1

Down syndrome

Answer 1

ALL/acute lymphocytic leukemia (we ALL fall Down), AML/acute myelocytic leukemia

Question 2

Xeroderma pigmentosum, albinism

Answer 2

melanoma, basal cell carcinoma, and esp. squamous cell carcinomas of skin

Question 3

chronic atrophic gastritis, pernicious anemia, postsurgical gastric remnants

Answer 3

gastric adenocarcinoma

Question 4

actinic keratosis

Answer 4

squamous cell carcinoma of skin

Question 5

Barrett’s esophagus

Answer 5

esophageal adenocarcinoma

Question 6

tuberous sclerosis (facial angiofibroma, seizures, mental retardation)

Answer 6

astrocytoma, angiomyolipoma, and cardiac rhabdomyoma

Question 7

Plummer-Vinson syndrome (atrophic glossitis, esophageal webs, anemia; all due to iron deficiency)

Answer 7

squamous cell carcinoma of esophagus

Question 8

cirrhosis (alcoholic, hepatitis B or C)

Answer 8

hepatocellular carcinoma

Question 9

ulcerative colitis

Answer 9

colonic adenocarcinoma

Question 10

Paget’s disease of bone

Answer 10

secondary osteosarcoma and fibrosarcoma

Question 11

imunodeficiency states

Answer 11

malignant lymphomas

Question 12

AIDS

Answer 12

aggressive malignant lymphomas (non-Hodgkin’s) and Kaposi’s sarcoma

Question 13

autoimmune diseases (e.g., Hashimoto’s thyroiditis, myasthenia gravis)

Answer 13

lymphomas

Question 14

acanthosis nigrans (hyperpigmentation and epidermal thickening)

Answer 14

visceral malignancy (stomach, lung, breast, uterus)

Question 15

dysplastic nevus

Answer 15

malignant melanoma

Question 16

radiation exposure

Answer 16

sarcoma, papillary thyroid cancer