Disease Peripheral Blood Smears Flashcards

1
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Iron Deficiency Anemia

Characterized by hypochromatic and microcytic RBCs

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2
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Thalassemia

Characterized by poikilocytosis, target cells, and nucleated red cells

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3
Q
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B12/Folate Deficiency

Characterized by oval macrocytes, anisocytosis, poikilocytosis, hypersegmented neutrophils, decreased platelets

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4
Q
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Lead Poisoning

Characterized by basophilic stipiling

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5
Q
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Sideroblastic anemia

Characterized by dimorphic population of RBCs, anisocytosis, and poikilocytosis

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6
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7
Q
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Hereditary spherocytosis

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8
Q
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Hereditary elliptocytosis

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9
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Sickle Cell Anemia

Characterized by sickle cells, poikilocytosis, target cells

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10
Q
A

Schistocytes, can be associated with trauma from a malfunctioning mechanical valve

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11
Q
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Antibody mediated

Characterized by microspherocytes and nucleated RBCs

Antibody tagged RBCs are partially “eaten” by macrophages and turn into spherocytes

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12
Q
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RBC clumps due to cold autoantibodies. These can be sequelae of infections like mycoplasma or EBV

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13
Q
A

Reactive Lymphocytes = infectious mononucleosis

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14
Q
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Cleaved lymphocytes = bordatella pertussis

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15
Q
A

Borrelia, causes relapsing fever

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16
Q
A

Chronic myelogenous leukemia

increased neutrophils, basophils, platelets, and myeloid precursors

17
Q
A

Myelodysplastic syndrome

Characterized by hypogranular platelets, macrocytic RBCs, pseudo-Pelger Huet cells, blasts

18
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Polycythemia vera

Characterized by anisocytosis, poikilocytosis, occasional nucleated RBCs, increased neutrophils, basophils, and platelets

19
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Agnogenic Myeloid Metaplasia

immature erythroid and myeloid cells, teardrop cells

20
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Acute Lymphoblastic Leukemia

21
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22
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Acute Lymphoblastic Leukemia

myeloblasts, sometimes with an Auer rod

23
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Chronic Lymphocytic Leukemia

increased small lymphocytes with coarsely clumped chromatin, smudge (basket) cells

24
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A

Prolymphocytic leukemia

25
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26
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Hairy cell leukemia

lymphocytes with filamentous cytoplasmic projections and oval or folded nuclei (hairy cells)

27
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