Digestive System Chap.22 Flashcards
Digestive system
( Definition)
Breaks down food into nutrients that can be absorbed by the bloodstream and deliver to body cells in usable form.
GI stand for?
Gastrointestinal track
Alimentary canal
What does it consist of? (6things)
🔸️Oral cavity (mouth)
🔸️Pharynx
🔸️Esophagus
🔸️Stomach
🔸️Small intestine
🔸️Large intestine
Accessory organs
(Definition)
Located around alimentary canal and assistant in digestion
Accessory organs
(Consist of? 6things)
Teeth
Tongue
Salivary glands
Liver
Gallbladder
Pancreas
Digestive function main process
( Six processes are?)
Ingestion
secretion
propulsion
digestion
absorption
defecation
Ingestion
( Definition)
Bring food and water into mouth
Secretion
( Definition)
Mucus, enzymes, acid, And hormones
Propulsion
( Definition)
Peristalsis
Pushing of food through organs
Digestion happens by….
(2 ways ur body digest food)
Mechanical and chemical
Absorption
(Definition)
Through wall of aliementary canal into blood or lymph
Defecation
( Definition)
Eliminate waste product
Mobility is…
A key process in every region of alimentary canal
What is skeletal muscle in the alimentary canal?
(4 things)
Oral cavity
Pharynx
Superior esophagus
Last portion of large intestine
Is two types of mixing & churning propulsion are…
Nervous ANS (autonomic nervous system)
Endocrine
Nervous ANS consist of 2 systems. What are they?
SNS (sympathetic nervous system) inhibits
PSN (parasympathetic nervous system) stimulates
Endocrine is…
Secrestion of hormones that stimulate or inhibit
Lumen
( Definition)
Concentric layers of tissues surrounding a space
Lumen Has 4 layers.
What are they?
Mucosa
Submucosa
Muscularis externa
Serosa / adventitia
Musco of the Lumen is made of…
(3 things)
Epithelium (simple columnar/ stratified squamous)
Lamina propria (connective tissue)
Muscularis mucosae (SMC smooth muscle cells)
Submucosa is…
Dense irregular connective tissue with blood vessels and submucosal glands
Submucosal plexus
Muscularis externa is…
🔸️Inner circular SMC
🔸️Outer longitudinal SMC
🔸️Myenteric
Serosa is…
🔸️Loose Connective tissue 🔸️Simple Squamous epithelium
Submucosal plexus
What does it do?
Regulates secretions
Myenteric plexus
What does it do?
Regulates motility
Serosa is…
Visceral peritoneum
Within peritoneal cavity
Simple Squamous Epithelium and loose connective tissues
Adventitia is…
Outside peritoneal cavity
Dense irregular connective tissue
Mensenteries
(Definition)
Folds of visceral peritoneum between loops of intestines.
Greater Omentum
Fatty apron that hangs from base of stomach (greater curvature)
Lesser Omentum
Attaches the Lesser curvature of the stomach to the liver
Oral cavity
( Accessory organs)
Teeth
Tongue
Salivary glands
Bolus
( What is it?)
A ball made of saliva and chewed food
Structure of oral cavity
( 6 things)
Cheecks (buccinator muscle)
Lips
Vestibule
Gums (gingiva)
Palate (hard and soft palate)
Uvula
Hard Palate is made of?
Maxilla and palatine bone
Soft Palate is made of?
Skeletal muscle
Uvula does?
Prevents food from entering the nasal cavity.
Mastication
(Definition)
Chewing that increases are surface area of food
Tooth structure
Crown and Root
Crown is located and made out of…
Located above the gum line and made of enamel and Dentin
Root is located and made out of…
Located below, the gum line is made of pulp (blood vessels and nerves)
The tongue is made of…
Skeletal muscle
Stratified Squamous epithlial
Lingual frenulum is?
Attaches tongue to floor of oral cavity
Papillae is?
Name 2 types of papillae
Bumps on the surface of the tongue
Filiform and taste buds
The Salivary glands are… (3 glands)
🔸️Parotid gland
🔸️Submandibular
🔸️Sublingual
Parotid gland
(Location & Function)
Located over masseter muscle
Produces enzymes and water
Submandibular gland
(Location & Function)
Along mandible
Produces mucus and enzymes
Sublingual gland
(Location & Function)
Inferior to tongue
Produces mainly mucus and some enzymes
Salivary amylase
An enzyme that initiates CHO digestion
Lysozyme
Enzyme that kills bacteria
IgA is
Antibody that destroys pathogens
Bicarbonate
Neutralizes acid
Pharynx
(Definition)
Passage way for 2 systems respiratory and digestion
The 3 areas of the Pharynx are?
Nasopharynx (nose)
Oropharynx (mouth)
Laryngopharnx (throat)
Function of Pharynx
Deglutition passes bolus through into esophagus
The Pharynx is surrounded by what 3 skeletal muscles?
Skeletal muscle called upper, middle, and lower pharyngeal constrictor muscles
Tonsils
(Definition)
Defense the body from pathogens that have entered nasal or oral cavities
There are 3 types of tonsils.
What are they?
Palatine tonsils
Lingual tonsils
Pharyngeal tonsils
Palatine tonsils
(Location)
Posterior oral cavity on either side of tongue.
Lingual tonsils
(Location)
Located under base of tongue
Pharyngeal tonsils
(Location)
Located on posterior wall of nasopharynx
Esophagus
(Function)
To transport bolus from Pharynx to stomach and prevent acid reflux
Esophagus
(Function)
🔸️To transport bolus from Pharynx to stomach
🔸️propulsion
🔸️mucus secretion
Esophagus
Is made of?
🔸️Mucosa :Stratified Squamous non keratinized epithelium
🔸️Superior:Skeletal muscle
🔸️Middle: Skeletal & Smooth
🔸️Inferior: Smooth muscle cells
Gastroesophageal sphincter
What does it do?
Known as the LES (lower esophageal sphincter)
Regulate passage of bolus into stomach and prevent reflux
Esophageal hiatus
Is opening in diaphragm
Swallowing/ Deglutition
(Function)
Propulsion, that pushes bolus of food from oral cavity through Pharynx and a esophagus to stomach
Swallowing/ Deglutition
What are the 3 phases?
Voluntary phase
Pharyngeal phase
Esophageal phase
The stomach has 5 regions.
What are they?
Cardia
Fundus
Body
Pyloric antrum
Pylorus
Rugae
The Cardia of the stomach (function)
Receives bolus when LES ( Lower esophagus sphincter) relaxes
The Fundus of the stomach is
Upper left domed-shape
The Body of the stomach is
Largest section
The pyloric antrum of the stomach
Is the inferior portion of the stomach
The pylorus of the stomach
Connect the duodenum via pyloric sphincter
The Rugae of the stomach
Is the folds found in undistended stomach
Greater curvature
Convex left side (bottom of stomach)
Lesser curvature
Concave right side ( Upper side stomach)
Chyme
Mixture of bolus and stomach secretion
Goblet cells
Secrete a thick mucus
Gastric glands
Found at base of gastric pits
Gastric juice
An enzyme containing fluid that contains endocrine cells that secrete hormones and acidic
The stomach has 4 main cell types. What are they ?
Enteroendocrine cells
Chief cells
Parietal cells
Muscous neck cells
Enteroendocrine cells
(Stomach)
Also known as G cells, secrete hormone gastrin that simulates secretions
Chief cells
Create the hormone pepsinogen
Pepsinogen (hormone)
Pre cursor to enzyme pepsin , which begins protein digestion
Parietal cells
Create hydrochloric acid (HCl)
Muscous neck cells
(Stomach)
Secrets acidic mucus
Intrinsic factor (IF)
is a glycoprotein produced by the parietal cells in the stomach lining. It plays a crucial role in the absorption of vitamin B12 and the formation of RBC
Phases of gastric secretions
(3 phases)
Cephalic phase
Gastric phase
Intestinal phase
Cephalic phase
Triggered by sight, smell, taste, or thought of food.
PSN Triggers gastric juice secretion
Gastric phase
Triggered by food and stomach.
Gastrin released
Gastric juice secreted
Intestinal phase
Triggered by food moving into small intestine
Intestinal gastrin released => Secretion of gastric juice
Small intestine
What does it do?
Secretion, digestion, absorption, and propulsion
3 regions of the small intestine
Duodenum
Jejunum
Ileum
Duodenum
First region of the small intestine
Major duodenal papilla - Receives secretion from gallbladder and pancreas
Duodenal glands => alkaline mucus
Jejunum
Middle region of small intestine
Most chemical digestion and absorption
Ileum
Last region of small intestine
Ends at ileocecal valve
Intraperitoneal
Intraperitoneal
the administration of substances directly into the peritoneal cavity, the space between the peritoneum and the abdominal organs.
Structure of the small intestine
(3 Structures)
Circular folds (plicae circulares)
Villi
Microvilli (brush border)
Circular folds (plicae circulares)
( Small intestine)
Mucosa and submucosa of small intestine
Slow transition of chyme to give enterocytes more time to absorb nutrients
Villi
Layer of entrocytes surrounding blood capillaries and lymphatic vessels (lacteal)
Microvilli (brush border)
modification of plasma membrane of enterocytes
The types of movements of the small intestine
Peristalsis
Segmentation (mechanical digestion)
Large Intestine
🔸️Receives material from small intestine that are not digested or absorbed
🔸️secretion of mucus, proportion, and defication
🔸️Absorbs water and electrolytes
Large intestine anatomy
(4 parts)
Cecum
Colon
Rectum
Anus
Cecum
Veriform appendix contains lymphatic nodules
Colon (4 parts)
Ascending colon
Transverse colon
Descending colon
Sigmoid colon
Rectum
Has rectal valves are horizontal folds that hold feces in
Anal canal
🔸️Internal anal sphincter (PSN)
🔸️External anal sphincter (Levator ani muscle)
Taeniae coli is made of…
(L.I)
3 bands of SMC
Haustra (L.I)
Pockets or saccules
Epiploic appendages
(L.I)
Fat filled pouches of serosa
Goblet cells do what?
(L.I)
Are Protective and lubricating mucus
Bacteria in large intestine
🔸️Normal flora have symbolic relationship
🔸️Product Vit.K (Clotting)
🔸️Metabolize undigested material
🔸️Deter growth of pathogen
Simulate immune health
2 Types of mobility of L.I.
Segmentation (churring)
Mass peristalsis
Defication reflex
PSN
Relaxation of internal and external anal sphincters, contraction of SMC
Diarrhea
Increase mobility, not having enough time to absorb water produces watery feces
Constipation
Mobility decreases too much water absorption and fecal material becomes hard
Pancreas
Both endocrine and Exocrine functions
Pancreas releases what hormones? (Endocrine)
Insulin (decrease BG)
Glucagon (increase BG)
Pancreatic juice(exocine) enzymes secreted by
Acini cells
(Produce, store, & release digestive enzyme)
Pancreatic juice is made out of
Bicarbonate ions
Pancreatic amylase
Pancreatic lipase
Trypsin, chymotrypsin, carboxypeptides
Nucleases
Cholecystokinin (CCK) (duodenum)
Stimulates pancreatic enzymes
Inhibits gastric glands
Stim. G.B. to release bile
Secretin (duodenum)
Stimulates pancreatic juice rich in bicarbonte
Increases bile production in Liver
GIP
inhibits gastric activity
(Gastric inhibitory polypeptide)
Liver is covered by…
A thin CT capsule
4 lobes of the liver
🔸️right
🔸️left
🔸️caudate
🔸️quadrate
falciform ligament
🔸️separates right and left lobes of the liver
round ligament:
remnant of umbilical vein
Liver lobule
- basic unit of liver
-composed cords of hepatocytes arranged around a central vein →
hepatic v. IVC
-hepatic sinusoids drain hepatic portal vein and hepatic artery
Functions of liver
Hepatocytes
Nutrient metabolism
Detoxification
Excretion
Hepatocytes
What are they and their function?
primary functional cells of the liver and produce bile
Detoxification
detoxifies substances produced by body, and substances that we eat or drink
Excretion of the liver is…
- directly excretes bilirubin in bile, antibiotics and other
substances liver processes
Gallbladder
.small sac on posterior liver
.Stores and concentrates bile
.CCK triggers contraction of SMC causing release bile into cystic duct
.Cystic duct joins with common hepatic duct (Common bile duct)
CCK
causes contraction of G.B.
Relaxation of h-p sphincter
Secretin of the gallbladder
stimulates bile production
Salivary amylase (salivary glands)
-initiates CHO digestion in mouth
- inactivated in stomach due to low pH
Pancreatic amylase (exocrine pancreas)
picks up CHO digestion in duodenum
Lactase, maltase, sucrase (brush border enz. S.I.)
breaks down disaccharides into monosaccharides
Lactose turns into
Lactose→ G(glucose) +galactose
Maltose turns into
Maltose → G(glucose) +G (glucose)
Sucrose into
Sucrose → G(glucose) + fructose
Proteins get digested into
Amino acids
Pepsinogen become
pepsin (req. pH 2)
Trypsin
(activated by brush border enz.)
- from trypsinogen (pancreas)
Chymotrypsin (pancreas)
Carboxypeptidase (pancreas)
Digestion & absorption of proteins
Pepsin (stomach)
Trypsin (pancreas)
Carboxypeptidase (pancreas)
Chymotrypsin (pancreas)
Digestion & absorption of lipids
Triglycerides
Gastric lipase (stomach)
Pancreatic lipase (pancreas)
Chylomicrons
Triglycerides
→ glycerol + F.A (fatty acid)
Bile salts cause emulsification of lipids
Digestion & absorption of nucleic acids
Nucleic acids (DNA, RNA) → nucleotides
Nucleases (pancreas)
ABSORPTION OF WATER, ELECTROLYTES, AND VITAMINS
9 L. H2O enters S.I. each day
-2 L. of water are ingested
-7 L. secreted into alimentary canal
Of the 9 liters, about 8 liters are absorbed into enterocytes of S.I.
Most of remaining water is absorbed into enterocytes of L.I., leaving only about 0.1 liter of water to be excreted in feces
Enterogastric reflex
Is triggered as chyme enters duodenum, declining pH (more acidic) and presence of lipids trigger
Enterogastric reflex
(What happens? 5 things)
🔸️Emptying function
🔸️Liquids move rapidly
🔸️Solids must be converted to a nearly liquid state before entering S.I.
🔸️High lipid chyme delays gastric emptying
🔸️Duodenum needs to process incoming chyme (mix with HCO3 and H₂O)
Uvula
Prevents food from entering nasal cavity
Lips are made out of…
🔸️Orbicularis oris muscle
🔸️Stratified Squamous keratinized epithlium
Esophagus is located
Posterior to trachea