Digestion and absorption of fats L5 Flashcards

1
Q

Fats broken into

A

triglycerides and phospholipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

structure of triglycerides

A

3 fatty acids ester bonded to glycerol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

unsaturated fatty acids contain

A

double bonds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

saturated fatty acids contain

A

no double bonds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what do phospholipids come from

A

cell membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

cholesterol esters come from

A

animal cell fat stores

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

cholesterol comes from

A

animal cell membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

TAG=

A

triaglycerol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

in water TAG is

A

immisible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What needs to happen to TAG for digestion

A

emulsified by bile salts and amphipathic lipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

amphipathic=

A

hydrophobic and hydrophillic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What happens to TAG in the mouth and stomach

A

TAG is emulsified and split into droplets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

how are the TAG droplets stabilised

A

in the gall bladder (by bile salts)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what temp is required for emulsification

A

37 degrees

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

why is TAG split into droplets

A

increase surface area for enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what do the bile salts and amphipathic lipids do

A

coat small emulsion particles preventing them re-aggregating into bulk TAG phase

17
Q

what does lipase do

A

degrade TAG

18
Q

where does most lipase fat digestion happen

A

pancreatic —> small intestine

19
Q

3 sources of lipase

A

lingual lipase
gastric lipase
pancreatic lipase

20
Q

what does churning of the stomach do

A

at 37 degrees emulsifies bulk TAG phase

21
Q

what are micelles

A

bile salts surrounding long-chain fatty acids and monoglycerides

22
Q

where do micelles travel to

A

the apical brush boarder of intestinal epithelial cells

23
Q

what do micelles release at apical brush boarder

A

products for digestion

24
Q

what happens inside the epithelial cells of the intestine

A

long chain fatty acids and monoglycerides are recombined to form triglycerides

25
what are chylomicrons
TAG aggregated to, phospholipids, cholesterol and get coved in proteins
26
how do chylomicrons exit the epithelial cell
via exocytosis
27
how do chylomicrons enter the rest of the body
via lacteals (lympathic vessels) and eventually via the left subclavian vein
28
where is bile formed
the liver
29
where is bile stored and concentrated
gallbladder
30
what are bile acids
the break down products of cholesterol
31
what are the primary bile acids (2)
cholic acid | Chenodeoxycholic acid
32
what stimulates the gallbladder to release bile
CCK from the duodenal mucosa
33
what normally prevents bile release into the intestine
sphincter of oddi
34
risk factor for gall stones
female caucasion high cholesterol over weight
35
what is an enterocyte
cell of the intestinal lining
36
where is lingual lipase released from
ebners glands on dorsal surface of tongue
37
what is most TAG degraded to
2-monoacylglycerol (2-MAG)