Diff17 - 18

Question 1

What is the first step in imaginal disc transformation?

Answer 1

Axis formation

Question 2

What specifies the posterior compartment of an imaginal disc?

Answer 2

Engrailed

Question 3

What does engrailed induce?

Answer 3

Hh expression

Question 4

What does Hh expression induce?

Answer 4

Dpp expression

Question 5

What is Dpp?

Answer 5

Decapentaplegic - drosophila TGF-b homologue

Question 6

What does Dpp interact with?

Answer 6

Tkv/Pnt on surface - a heterodimer

Question 7

What transcription factor does Dpp induce?

Answer 7

Mad

Question 8

What does Mad TF transcribe?

Answer 8

Omb/sal

Question 9

What do lower levels of Dpp induce?

Answer 9

Only Omb expression

Question 10

How is the Y axis formed?

Answer 10

Morphogen - apterous; wng/wnt signalling pathway

Question 11

What patterns proximal/distal axis?

Answer 11

Hh > dorsal Dpp and ventral Wg > distalless (DLL)

Question 12

What two homeodomains are expressed to create distal/proximal pattern?

Answer 12

Dll and homothorax (Hth)

Question 13

What do Dll and Hth do?

Answer 13

Cooperate to induce TFs such as Dachous

Question 14

What is the mammalian Hh homologue?

Answer 14

SHh

Question 15

What is the mammalian Wg homologue?

Answer 15

Wnt7a

Question 16

What is the mammalian Ap homologue?

Answer 16

Lmx1

Question 17

What is the mammalian Hth homologue?

Answer 17

Meis

Question 18

What is the mammalian Dll homologue?

Answer 18

Hoxd13