Diff15 - 24 Flashcards
Describe the segmentation in drosophila
Obvious - A1-8, T1-3, three head
Define what is meant by long term band insect
All 14 segments defined simultaneously
What is the outcome of long term band development?
Very very quick - 24 hours
What is the benefit of long term band development?
Developed and ready before food source disappears
What is the downside of long term band developmnet?
Complicated - interaction of all genes required for every segment
Characterise a knirps mutant
“Little boy” - creates a gap in the embryo
Characterise a paired mutant
Deletion of even number segments (halving length)
Characterise an odd-paired mutant
Deletion of odd number segments (halving length)
Characterise a goosebury mutant
Covered in spines of naked cuticle
What are the five classes of genes?
Maternal, gap, pair, segment polarity and selector
Name a maternal gene
Bicoid
What is bicoid?
Maternally loaded DNA binding transcriptional activator
Characterise a bicoid mutant
Fine - maternal bicoid covers, but progeny have no head
Outline bicoid segementation
Like accordian, based on dosage (high = pushed more posteriorly)
Outline French flag model