Diff15 - 24 Flashcards

1
Q

Describe the segmentation in drosophila

A

Obvious - A1-8, T1-3, three head

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2
Q

Define what is meant by long term band insect

A

All 14 segments defined simultaneously

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3
Q

What is the outcome of long term band development?

A

Very very quick - 24 hours

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4
Q

What is the benefit of long term band development?

A

Developed and ready before food source disappears

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5
Q

What is the downside of long term band developmnet?

A

Complicated - interaction of all genes required for every segment

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6
Q

Characterise a knirps mutant

A

“Little boy” - creates a gap in the embryo

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7
Q

Characterise a paired mutant

A

Deletion of even number segments (halving length)

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8
Q

Characterise an odd-paired mutant

A

Deletion of odd number segments (halving length)

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9
Q

Characterise a goosebury mutant

A

Covered in spines of naked cuticle

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10
Q

What are the five classes of genes?

A

Maternal, gap, pair, segment polarity and selector

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11
Q

Name a maternal gene

A

Bicoid

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12
Q

What is bicoid?

A

Maternally loaded DNA binding transcriptional activator

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13
Q

Characterise a bicoid mutant

A

Fine - maternal bicoid covers, but progeny have no head

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14
Q

Outline bicoid segementation

A

Like accordian, based on dosage (high = pushed more posteriorly)

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15
Q

Outline French flag model

A
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16
Q

Outline segment polarity

A

Hh & Wg feedback onto each other to maintain each others expresion and refine segment borders

17
Q

What creates naked cuticle between segments?

A

Wg

18
Q

What is required for Wg?

A

Hh

19
Q

What does a loss of Hh create?

A

Absence of Wg, hairs everyewhere

20
Q

Outline the role of selector genes

A

Hox genes - who am I information for each segment

21
Q

What controls selector genes?

A

Combination of gap and pair-rule genes

22
Q

Example of short germ band insect

A

Strigamia maritime - centipede

23
Q

Outline strigamia maritime segmentation

A

Embryonic separation into three main areas - head, trunk, transition, posterior disc. Starts with head, adds abdominal segments sequentially

24
Q

Draw the strigamia maritime delta-notch feedback oscillator

A