Diff14 - 13 Flashcards
How long is the drosophila life cycle at 25 degrees?
10 days
How long is the drosophila life cycle at 18 degrees?
21 days
What was the first mutant drosophila discovered?
White eyed - 1910
What was the big breakthrough in drosophila research?
Christiane Nusslein-Volhard and Eric Weischaus identifyin genes in development and patterning of larval cuticle
When was the drosophila fully mapped?
2006
How many species of drosophila have now been sequenced?
21
What cells secrete spermatogenesis factors?
Hub cells
What signals do hub cells secrete?
Unpaired etc via JAK/STAT pathway
Outline oogenesis stem cell maintenance in drosophila
4 incomplete cystoblast meitotic dvisions, selection of future oocyte, endo-reduplication by nurse cells, oocyte meiotic recombination, egg activation meiosis I & II
What do nurse cells do?
Endo-reduplication
What is endo-reduplication?
DNA replication without cytokinesis
Where is the maternal DNA in drosophila?
Proteins & RNAs made in nurse cells and transferred into developing oocyte
What is the process of transferring maternal DNA into the developing oocyte in drosophila called?
Cytoplasmic dumping via ring canals