Diff14 - 13 Flashcards

1
Q

How long is the drosophila life cycle at 25 degrees?

A

10 days

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2
Q

How long is the drosophila life cycle at 18 degrees?

A

21 days

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3
Q

What was the first mutant drosophila discovered?

A

White eyed - 1910

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4
Q

What was the big breakthrough in drosophila research?

A

Christiane Nusslein-Volhard and Eric Weischaus identifyin genes in development and patterning of larval cuticle

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5
Q

When was the drosophila fully mapped?

A

2006

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6
Q

How many species of drosophila have now been sequenced?

A

21

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7
Q

What cells secrete spermatogenesis factors?

A

Hub cells

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8
Q

What signals do hub cells secrete?

A

Unpaired etc via JAK/STAT pathway

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9
Q

Outline oogenesis stem cell maintenance in drosophila

A

4 incomplete cystoblast meitotic dvisions, selection of future oocyte, endo-reduplication by nurse cells, oocyte meiotic recombination, egg activation meiosis I & II

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10
Q

What do nurse cells do?

A

Endo-reduplication

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11
Q

What is endo-reduplication?

A

DNA replication without cytokinesis

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12
Q

Where is the maternal DNA in drosophila?

A

Proteins & RNAs made in nurse cells and transferred into developing oocyte

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13
Q

What is the process of transferring maternal DNA into the developing oocyte in drosophila called?

A

Cytoplasmic dumping via ring canals

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