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109 maternal > Dic > Flashcards

Dic Flashcards

1
Q

organs that affected in Dic

A

liver
brain
kidneys

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2
Q

conditions associated with dic

A

premature separation of the placenta
hpn of pregnancy
amniotic fluid embolism
placental retention
septic abortion
retention of dead fetus

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3
Q

factor I

A

Fibrinogen

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4
Q

converts into fibrin to form the clot

A

Fibrinogen

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5
Q

Factor II

A

Prothrombin

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6
Q

converts into thrombin which activates fibrinogen

A

Prothrombin

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7
Q

Factor III

A

Tissue Factor/ Thromboplastin

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8
Q

Triggers the clotting cascade after injury

A

Tissue Factor/ Thromboplastin

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9
Q

Factor IV

A

Calcium

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10
Q

essential for clotting reactions

A

Calcium

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11
Q
A
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11
Q

Factor V

A

Labile Factor

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12
Q

Works with factor x to convert prothrombin to thrombin

A

Labile Factor

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13
Q

Factor VII

A

Stable Factor

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14
Q

activates factor x in the presence of tissue factor

A

Stable Factor

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15
Q

factor VIII

A

anti hemophilic factor A

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16
Q

helps factor IX in activating factor X

A

anti hemophilic factor A

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17
Q

Factor IX

A

Christmas Factor/ anti hemophilic factor b

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18
Q

works with factor VII to activate factor X

A

Christmas Factor/ anti hemophilic factor b

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19
Q

Factor X

A

Stuart Prower Factor

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20
Q

converts prothrombin to thrombin starting the common pathway

A

Stuart Prower Factor

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21
Q

Factor XI

A

Plasma Thromboplastin Antecedent

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22
Q

activates factor ix in the clotting cascade

A

Plasma Thromboplastin Antecedent

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23
Q

Factor XII

A

Hageman factor

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24
initiates the intrinsic pathway of clotting
Hageman factor
26
Factor XIII
Fibrin stabilizing factor
27
strengthens and stabilizes the fibrin clot
Fibrin stabilizing factor
28
29
instrinsic pathway
contact activation (surface damage)
30
31
instrinsic pathway
FACTOR 12,11,9,8
32
33
34
serious disorder in which the proteins that control blood clotting becomes overactive
DIC
35
organs can affect dic
liver,brain and kidneys
36
components of blood
plasma WBC platelet RBC
37
Factor 1
Fibrinogen
38
converts into fibrin to form clot
fibrinogen
39
41
extrinsic pathway
tissue factor released in trauma + inflammation
42
extrinsic pathway
Factor 3,7
43
Common pathway
Factor 10, 1, 2
44
happened rapidly coagulopathy is dominant bleeding and shock seen in severe infection and fluid embolism
acute DIC
45
happened slowly and last several weeks, thrombosis and clotting may predominate mainly seen in cancer
Chronic DIC
46
paradox of DIC
Increased coagulation in one point of circulatory system Bleeding defect, Throughout the rest of the system
47
normal platelet count
150,000- 450,000 ul
48
<150,000 platelets
thrombocytopenia
49
>450,000
Thrombocytosis
50
early signs of dic
• unexplained bleeding (gums,IV sites,surgical wounds) • petechiae or purpura • low blood pressure (shock)
51
severe signs of dic
massive postpartum hemorrhage organ dysfunction
52
conditions that are associated in the development of dic
• premature separation of the placenta • hypertension of pregnancy • amniotic fluid embolism • placental retention • septic abortion • retention of a dead fetus
53
causes of dic
Inflammation from an infection • Injury or illness • Extreme bleeding • Sepsis
54
therapeutic management dic
• Heparin (IV) • Blood and platelet (fresh frozen plasma) transfusion • Antithrombin Ill factor, fibrinogen, or cryoprecipitate
55
diagnostic exam dic
decreased platelet decreased fibrinogen decreased factor VI (proaccelerin) decreased VIII (antihemolytic factor)
56
bleeding time
prothrombin time
57
slow and strong hold
intrinsic
58
fast and temporary
extrinsic
59
major component of blood clotting
Fibrin
60
normal breakdown of clotting
fibrinolysis
61
factor III
Tissue Factor/Thromboplastin

109 maternal (14 decks)

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