Diarrhea Flashcards

1
Q

Problem based approach with diarrhea

A

Define the problem, location, system, then lesion

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2
Q

Alteration in normal pattern of defecation

A

Soft, unformed stools
↑ fecal water content
↑ frequency of defecation

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3
Q

Defining the location

A

Small bowel, large bowel or mixed

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4
Q

Small bowel diarrhea characteristics

A

Large amount
Melena or partial digestion of blood
WL with chronic
Borborygmus and flatulence
If unwell dehydrated

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5
Q

Large bowel diarrhea

A

Small amounts frequently with inflamed bladder
Mucus (hallmark) and fresh blood
Tenesmus (straining)

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6
Q

Secondary GI disorders causing diarrhea

A

Hepatic disease, pancreatic insufficiency, pancreatitis, hyperthyroidism, hypoadrenocorticism, renal disease

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7
Q

Large bowel or mixed bowel diarrhea as major presenting signs indicates _____________

A

Primary GI lesion

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8
Q

Secondary GI disease most frequently has characteristics of _____________

A

small bowel disease

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9
Q

Parasites and protozoa causing acute small bowel diarrhea

A

Parasites- ascarids, hookworms
Protozoa - giardia, coccidia

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10
Q

Diet related causing acute small bowel diarrhea

A

Overeating (pups)
Dietary change
Spoiled food
Garbage

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11
Q

Bacterial disease causing acute small bowel diarrhea

A

Campylobacter (young only, mixed bowel, zoonotic)
Salmonella (raw food, zoonotic)
Clostridium difficile
E. coli

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12
Q

Infection causing acute small bowel diarrhea

A

Viral enteritis- parvo, corona and rota

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13
Q

Acute Hemorrhagic diarrhea syndrome (AHDS)/ Hemorrhagic Gastroenteritis (HGE)

A

Acute onset of bloody diarrhea (small bowel)
Significant hemoconcentration (↑ PCV) with normal or low plasma protein
Typically in small breeds

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14
Q

What is Acute Hemorrhagic diarrhea syndrome (AHDS) caused by?

A

Novel necrotising toxin produced by Type A Clostridia perfringens (antimicrobial therapy doesn’t work)

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15
Q

Parasites causing chronic small bowel diarrhea

A

Toxocara- roundworms
Ancylostoma (hookworms)
Visceral larval migrans

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16
Q

Diet related causing chronic small bowel diarrhea

A

Lactose intolerance (common)
Gluten intolerance (uncommon)
Dietary hypersensitivity/ intolerance (common)

17
Q

Bacteria and protozoa causing chronic small bowel diarrhea

A

Campylobacter
Clostridium
Giardia
Cryptosporidium (immunocompromised)
Coccidia (young)

18
Q

Dietary hypersensitivity

A

Chronic intermittent diarrhea, vomiting and pruritus
Allergens

19
Q

Pruritus species variation

A

Cats: ears, face
Dog: axillary region, feet

20
Q

Allergens species differences

A

Dog: beef, lamb, chicken, wheat (gluten)
Cat: fish, milk, diary

21
Q

Types of Chronic Enteropathy (IBD)

A

Diet response CE (most common)
Antibiotic response CE
Immunosuppressive responsive CE (real IBD)
Non-responsive CE

22
Q

Antibiotic responsive CE

A

Abnormal/unbalanced bacterial population
Abnormal gut reaction to normal bacterial population

23
Q

Chronic Enteropathy dietary trial

A

Novel protein or hydrolyzed (@ least 2 or 3 diets)
Total compliance
2-10 weeks a response
Harder in cats, keep them indoors

24
Q

Chronic Enteropathy treatment trials

A

If no response to dietary trial use metronidazole or tylosin
↑ fiber

25
Q

Neoplasia causing small bowel diarrhea

A

Diffuse lymphosarcoma
Adenocarcinoma
Mastocytoma

26
Q

Other diseases causing chronic small bowel diarrhea

A

Lymphangiectasia (primary or secondary)
Brush order enzyme biochemical defects

27
Q

Protein losing enteropathy (PLE)

A

When diffuse small intestinal disease results in excessive loss of serum proteins into the gut causing hypoproteinemia

28
Q

Causes of protein losing enteropathy

A

Immunosuppressive- responsive or non-responsive chronic enteropathy (IBD)
Lymphangiectasia
Lymphoma

29
Q

Most common clinical signs for protein losing enteropathy

A

GI signs (V/D)
WL
Ascites, pleural effusion, peripheral edema

30
Q

Parasites causing large bowel diarrhea

A

Trichuris vulpis (dogs)
Ancylostoma caninum (cutaneous larval migrans)

31
Q

Protozoa causing large bowel diarrhea

A

Giardia
Entamoeba spp.
Tritrichomonas foetus (cats)

32
Q

Bacteria causing large bowel diarrhea

A

Campylobacter
Clostridium
Salmonella spp.
Granulomatous colitis (boxers, frenchies)

33
Q

Diet related large bowel diarrhea

A

Toxicity (garbage)
Fiber-repsonsive
Dietary hypersensitivity/intolerance

34
Q

Causes of mixed bowel diarrhea

A

Giardia
Campylobacter
Tritrichomonas foetus (cats)
Dietary indiscretion/ intolerance/ hypersensitivity
AHDS
Inflammatory

35
Q

Diagnostic tools for diarrhea

A

Fecal tests (culture, float, panels, etc.)
Serum trypsin like immunoreactivity (TLI)
Cobalamin and folate
Ultrasound
Biopsy (endoscopy, laparotomy)