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PATH II > developmental and odontogenic cysts day 3 > Flashcards

developmental and odontogenic cysts day 3 Flashcards

1
Q

Orthokeratinizing Odontogenic Cyst
relation to OKC?
occurence?

A
  • A developmental odontogenic cyst with an orthokeratin lining, NOT parakeratin
  • Originally described as the “orthokeratinized variant of the odontogenic keratocyst”
  • Does not behave as an odontogenic keratocyst
  • no recurrence
  • not related to OKC
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2
Q

orthokeratinizing odontogenic cyst radio

A

well defined uniloc lucency

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3
Q

Orthokeratinizing Odontogenic Cyst histo

A

orthokeratin in lumen

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4
Q

Calcifying Odontogenic Cyst
(Gorlin Cyst)
* WHO classified as
* additional names
* location/demo
* radio
* key cell
* Sometimes associated with?

A
  • WHO: Calcifying Cystic Odontogenic Tumor
  • Gorlin cyst, calcifying and keratinizing odontogenic cyst
  • Anterior jaws of adults
  • Radiolucent to mixed
  • Ghost cells
  • Sometimes associated with odontomas
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5
Q

Calcifying Odontogenic Cyst
(Gorlin Cyst) locations

A
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6
Q
A

orthokeratinizing odontogenic cyst

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7
Q

dif dx?

A

Calcifying Odontogenic Cyst (Gorlin Cyst)
Ca epithelial odontogenic tumor
AOT
odontogenic fibroma

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8
Q

dif dx?

A

ca odontogenic cyst
ca epithelial odontogenic tumor
ameloblastic fibro-odontoma

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9
Q

Calcifying Odontogenic Cyst
(Gorlin Cyst) histo

A

possess non-nucleated epi cells= ghost cells

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10
Q
A

ghost cells= Calcifying Odontogenic Cyst
(Gorlin Cyst)

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11
Q
A

Calcifying Odontogenic Cyst
(Gorlin Cyst)
note: ghost cells and calcification present

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12
Q

Glandular Odontogenic Cyst
* defined
* locations, demo
* radio
* behavior / recurrence

A
  • Sialodontogenic cyst –an odontogenic cyst with glandular
    (salivary) features
  • Anterior jaws of middle-aged adults, mandible > maxilla
  • Commonly multilocular, crosses midline
  • Aggressive behavior - 30% recurrence
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13
Q

glandular odontogenic cyst radio

A

well defined multilocular radiolucency

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14
Q

Glandular Odontogenic Cyst histo

A

normal cyst histo with pseudoglandular spaces and cilia on epithelium with goblet cells present

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15
Q

biopsy from anterior maxilla of 50 y/o female, presented as a multilocular lucency crossing the midline

A

glandular odontogenic cyst

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16
Q

Biopsy from the anterior mandible of a 45y/o male presented as a multilocular lucency crossing the midline

A

glandular odontogenic cyst

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17
Q

SOFT TISSUE CYSTS

A

Nasolabial Cyst
Lymphoepithelial Cyst
Cervical Lymphoepithelial Cyst
Thyroglossal Duct Cyst

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18
Q

Nasolabial Cyst
* additional names
* location
* from
* demo

A
  • Nasoalveolar cyst, Klestadt cyst
  • Soft tissue cyst of upper lip lateral to midline
  • Developmental cyst, remnants of nasolacrimal duct
  • Adult females (3:1)
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19
Q

Nasolabial Cyst histo

A

cilia on epithleium with mucus cells present

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20
Q

NL cyst radio

A

none

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21
Q

Oral Lymphoepithelial Cyst
demo?
locations?

A
  • Cystic change of crypt epithelium of lymphoid aggregate
  • Young adults
  • Waldeyer’sring
  • Tonsillar pillar
  • Floor of mouth
  • Ventral tongue
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22
Q

oral lymphoepithelial cyst histo

A

lumen surrounded with epi and large conn tissue wall containing germinal centers or lymphoid aggregates

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23
Q

Cervical Lymphoepithelial Cyst

A
  • Branchial Cleft Cyst
  • Cystic change of branchial epithelium
  • Upper lateral neck anterior to border of sternocleidomastoid muscle in young adults
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24
Q

DST with cervical lymphoepithelial cysts

A

may occur with infection

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25
Cervical Lymphoepithelial Cyst histo
* Stratified squamous epithelial lining exhibiting lymphoid tissue with or without germinal centers in wall
26
cervical lymphoepithelial cyst radio
none
27
Thyroglossal Duct Cyst
* Cystic change of thyroglossal tract epithelium * Midline of neck in young people
28
thyroglossal duct cyst histo
follicles in conn tissue wall
29
thyroglossal duct cyst
30
PSUEDOCYSTS
***Lack epithelial lining*** Traumatic Bone Cyst Aneurysmal Bone Cyst Static Bone Cyst
31
Traumatic Bone Cyst additonal names
* Idiopathic bone cavity * Solitary bone cyst * Hemorrhagic bone cyst * Simple bone cyst * Unicameral bone cyst
32
Traumatic Bone Cyst structure? theory of origin?
* Empty cavity - not a true cyst, pesudocyst * Trauma-hemorrhage theory of origin
33
Traumatic Bone Cyst *demo * location * radio * outline * symptomatic * Expansion * teeth * Biopsy
* Male (2:1) * Teenagers –young adults * Mandible * Lucency * Scalloped border frequent * Asymptomatic * Expansion rare (20%) * Vital teeth * Biopsy initiates healing, little tissue and cells maybe bone fragments
34
traumatic bone cyst radio
35
Aneurysmal Bone Cyst *demo * growth, symptoms * location *radio
* Young individuals < 20 years * Rapidly growing, may blow out the cortex, painful * Mandible most commonly * Lucency, frequently multilocular
36
Aneurysmal Bone Cyst
37
how else could a aneurysmal bone cyst look on radio
unilocular
38
Surgical Findings Aneurysmal Bone Cyst *bone * blood * gross appearence * pigmentation
* Ballooning dilation of bone * Blood welling up from within the cavity, like a blood-soaked sponge * Fleshy aggregates of tumor surrounding cystic spaces filled with blood * Hemosiderin pigmentation
39
Aneurysmal Bone Cyst histo
* Not a true cyst * Cyst-like cavities, filled with blood (lots of RBC) * Multinucleated giant cells
40
biopsy, from a multilocular luceny in mandible
Aneurysmal Bone Cyst
41
biopsy, from a multilocular luceny in mandible
Aneurysmal Bone Cyst
42
Static Bone Cyst (Stafne Defect) * symptoms * Radio *etiology
* Asymptomatic * Radiolucency below inferior alveolar nerve canal * portion of Submandibular gland stuck in bone with man development
43
Static Bone Cyst (Stafne Defect) histo
resembles subman gland=mixed, mainly serous
44
Classes of ODONTOGENIC TUMORS
Epithelial Mesenchymal Mixed
45
epithelial odontogenic tumors
* Ameloblastoma * Adenomatoid Odontogenic Tumor * Calcifying Epithelial Odontogenic Tumor
46
* Mesenchymal derived odontogenic tumors
* Odontogenic myxoma * Odontogenic fibroma * Cementoblastoma *
47
mixed odontogenic tumors
* Odontoma * Ameloblastic Fibroma * Ameloblastic Fibro-odontoma
48
Spectrum of Odontogenic Tumors
49
Ameloblastoma radio app
can be multi or unilocular, mainly uniloc
50
Ameloblastoma defined? demo? location? recurrence? histo resembles what structure? does not form what tissue?
* An expansive, slow-growing, locally invasive lesion, typically of the posterior mandible of adults (mean = 35 y) * Recurrence is common but does not metastasize * * The histopathology of ameloblastoma recapitulates the enamel organ * Ameloblastoma does not form and hard tissue
51
ameloblastoma locations
52
dif dx
ameloblastoma OKC aneurysmal bone cyst
53
Histologic Types Ameloblastoma
* Solid: Follicular, Plexiform, Desmoplastic, Many more......... * Unicystic
54
The histopathology of ameloblastoma does not form?
The histopathology of ameloblastoma recapitulates the enamel organ * Ameloblastoma does not form and hard tissue
55
histo of ameloblastoma (high power)
odontogenic epithelium with basal cells possessing reverse polarity surrounding stellate reticululm
56
Follicular Ameloblastoma histo
same but with follicles containig the distinct ameloblastoma histo
57
Plexiform Ameloblastoma
similar to follicular but follicles form anastomoses
58
Desmoplastic Ameloblastoma * Location * density
* Anterior jaws, equally distributed between mandible and maxilla * Mottled mixed density with diffuse margins * Solid tumor with dense, collagenous stroma
59
desmoplastic ameloblastoma radio
can be mixed or opaque, dense fibrous conn tissue creates the opacity
60
what could this opacity be?
desmoplastic ameloblastoma
61
what type of ameloblastoma is this?
desmoplastic, dense fibrous conn tissue with compression of the odontogeic islands
62
peripheral vs central ameloblastomas
can arise in the jaw or at its periphery
63
Unicystic Ameloblastoma radio? location? demo age? recurrence?
* Cystogenic ameloblastoma * Unilocular pericoronal radiolucency, usually of posterior mandible –mimics a dentigerous cyst radiographically * 2nd to 3rd decades (Mean age = 18 y) * Recurrence uncommon
64
dif dx
unicystic ameloblastoma OKC dentigerous cyst
65
Unicystic Ameloblastoma(Vickers-Gorlin Change) histo
* Nuclear hyperchromatism * Nuclear palasading * Reverse polarity of basal cell nuclei * Subnuclear vacuolation
66
unicystic ameloblastoma, note the loose epithelium palasaded basal cells and reverse polarity of basal cells
67
* Sialodontogenic cyst –an odontogenic cyst with glandular (salivary) features * Anterior jaws of middle-aged adults, mandible > maxilla * Commonly multilocular, crosses midline * Aggressive behavior - 30% recurrence
Glandular Odontogenic Cyst * defined * locations, demo * radio * behavior / recurrence
68
normal cyst histo with pseudoglandular spaces and cilia on epithelium with goblet cells present
Glandular Odontogenic Cyst histo
69
cilia on epithleium with mucus cells present
Nasolabial Cyst histo
70
* Cystic change of crypt epithelium of lymphoid aggregate * Young adults * Waldeyer’sring * Tonsillar pillar * Floor of mouth * Ventral tongue
Oral Lymphoepithelial Cyst demo? locations?
71
lumen surrounded with epi and large conn tissue wall containing germinal centers or lymphoid aggregates
oral lymphoepithelial cyst histo
72
* Branchial Cleft Cyst * Cystic change of branchial epithelium * Upper lateral neck anterior to border of sternocleidomastoid muscle in young adults
Cervical Lymphoepithelial Cyst
73
* Stratified squamous epithelial lining exhibiting lymphoid tissue with or without germinal centers in wall from region anterior to SCM mm
Cervical Lymphoepithelial Cyst histo
74
* Empty cavity - not a true cyst * Trauma-hemorrhage theory of origin
Traumatic Bone Cyst structure? theory of origin?
75
* Male (2:1) * Teenagers –young adults * Mandible * Lucency * Scalloped border frequent * Asymptomatic * Expansion rare (20%) * Vital teeth * Biopsy initiates healing, little tissue and cells maybe bone fragments
Traumatic Bone Cyst *demo * location * radio * outline * symptomatic * Expansion * teeth * Biopsy
76
* Young individuals < 20 years * Rapidly growing, may blow out the cortex, painful * Mandible most commonly * Lucency, frequently multilocular
Aneurysmal Bone Cyst *demo * growth, symptoms * location *radio
77
* Not a true cyst * Cyst-like cavities, filled with blood (lots of RBC) * Multinucleated giant cells
Aneurysmal Bone Cyst histo
78
* Asymptomatic * Radiolucency below inferior alveolar nerve canal * portion of Submandibular gland stuck in bone with man development
Static Bone Cyst (Stafne Defect) * symptoms * Radio *etiology
79
resembles subman gland=mixed, mainly serous
Static Bone Cyst (Stafne Defect) histo
80
* An expansive, slow-growing, locally invasive lesion, typically of the posterior mandible of adults (mean = 35 y) * Recurrence is common but does not metastasize * * The histopathology resembles the enamel organ * does not form and hard tissue
Ameloblastoma
81
odontogenic epithelium with basal cells possessing reverse polarity surrounding stellate reticululm
histo of ameloblastoma
82
* Anterior jaws, equally distributed between mandible and maxilla * Mottled mixed density with diffuse margins * Solid tumor with dense, collagenous stroma
Desmoplastic Ameloblastoma * Location * density
83
* Unilocular pericoronal radiolucency, usually of posterior mandible –mimics a dentigerous cyst radiographically * 2nd to 3rd decades (Mean age = 18 y) * Recurrence uncommon
Unicystic Ameloblastoma
84
* Nuclear hyperchromatism * Nuclear palasading * Reverse polarity of basal cell nuclei * Subnuclear vacuolation
Unicystic Ameloblastoma(Vickers-Gorlin Change) histo

PATH II (32 decks)

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