common oral dx day 2 Flashcards
pyogenic granuloma lesion type
- A reactive vascular lesion - essentially a capillary hemangioma
pyogenic granuloma gender
Definite female predilection - vascular effects of hormones
pyogenic granuloma misnomer
Name is a misnomer. It is unrelated to infection. It is not
“pyogenic” and is not a true granuloma
pyogenic granuloma growth
may be rapid
where can pyogenic granulomas occur? most common site?
Gingiva most common site, but not limited to gingiva. It
occurs throughout the body on any skin or mucosal
surface
dif dx?
pyogenic grnauloma
PERIPHERAL OSSIFYING FIBROMA
PERIPHERAL GIANT CELL GRANULOMA
pyogenic granuloma histo
surface stratified squamous epithelium overlying a proliferation of endothelial lined channels mixed with acute and chronic inflammatory cells
pyogenic granuloma base?
sessile or pedunculated
pyogenic granuloma app
nodule located on the gingiva, can be lobulated, erthymatous/ mucosal colored
sessile/pedunculated
pyogenic granuloma effect on teeth?
can displace them
biopsy displayed endothelial hyperplasia along with A/C inflammatory cells within a strat squamous epithelium
pyogenic granuloma
Granuloma gravidarum
Pregnancy Tumor
* A clinical variant of pyogenic granuloma
* May involute without treatment post partum and undergo fibrous maturation
Peripheral Ossifying Fibroma
* lesion type
* demo age
* Not related to?
* Occurs exclusively where?
* histo?
* recurrence?
* effects on teeth?
- Reactive lesion – not a neoplasm
- Teenagers and young adults
- Not related to central ossifying fibroma
- Occurs exclusively on the gingiva
- Fibrous hyperplasia with osseous metaplasia - may
appear radio-opaque - May recur
- May move teeth
peripheral oss fibroma app
nodule on the gingiva, usually mucosal colored and sessile
capable of displacing teeth
dif
pyogenic granuloma
peripheral oss. fibroma
peripheral GCG
biopsy from a gingival nodule of 17 y/o, what could this be?
Peripheral oss. fibroma, fibrous hyperplasia along with osseous metaplasia
biopsy of a removed nodule from btwn two teeth, what is this?
peripheral oss fibroma
pano with a nodule on the gingiva, what could this be?
peripheral oss fibroma, calcification in the soft tissue
Peripheral Giant Cell Granuloma
* lesion type?
* age?
* Occurs exclusively where?
* Contains? may app?
* recurrence?
- Reactive lesion – not a neoplasm
- Older adults
- Occurs exclusively on gingiva and edentulous alveolar ridge
- Contains hemosiderin - may be bluish-purple
- May recur
PGCG app
nodule located on the gingiva, can appear colored due to hemosiderin, usually sessile in pictures shown
dif
pyogenic granuloma
per. oss. fibroma
PGCG
most likley dx out of the 3 P’s?
PGCG, coloration
how could PGCG be evidenced on a radiograph?
pressure resorb
biopsy from nodule on the gingiva of a 58 y/o, what is this?
PGCG
PGCG histo
strat squamous epithelium lining
conn tissue with multi nuc giant cells and RBCs
duct-like spaces present butn not mentioned?
Human Papilloma Virus potential dx’s?
- Squamous papilloma
- Verruca vulgaris
- Condyloma acuminatum
Squamous Papilloma
* #/ demo?
* app?
- Solitary lesion in adult (can be more than 1)
- Pedunculated, exophytic papule
- Numerous surface projections
dif
squamous papilloma
verruca vulgaris
dif
squamous papilloma
verruca vulgaris
Verruca Vulgaris
* where on body? age group?
* common presentation?
* oral mucosa?
very contagious spread
* Skin of hands in children
* Multiple, clustered lesions common
* White, verrucoid surface
* Autoinoculation of oral mucosa
Verruca Vulgaris
high risk HPVs
16 and 18
what lesions could look this way?
any HPV lesion
Condyloma Acuminatum
* transmission?
* common app?
* Low risk sub-types?
* High-risk sub-types?
- Venereal wart - sexually-transmitted disease
- Multiple, clustered lesions common
- Sessile, pink exophytic mass, larger than squamous
papilloma - Low risk sub-types 6 and 11 frequently found
(vaccine) - High-risk sub-types 16 and 18 may also be present
Virulence and Infectivity of Human
Papilloma Virus
Primary Herpetic Gingivostomatitis
*when?
* Generally occurs when?
* severity? why?
- Initial exposure to virus in an individual without immunity
- Generally occurs at young age after physical contact with infected individual
- Mostly subclinical disease - 80% of US population has antibodies to HSV
PRIMARY HERPES SIMPLEX INFECTION
Primary Herpetic Gingivostomatitis
Primary Herpetic Gingivostomatitis
* illness?
* Cervical sign?
- Flu-like illness with fever, malaise, arthralgia, headache
- Cervical lymphadenopathy
primary herptic gingivostomatitis
primary herpetic gingivostomatitis
where can HSV become dormant for secondary infection(s)
trigeminal ganglion
what is this likely?
recurrent herpes labialis
recurrent herepes labilalis
recurrent herpetic infection intraoral presentation
blisters/ulceration will occur on keratinized, non-moveable tissue
herpes blister structure
tzanck cells
virally infected dying cells with HSV infection
from an errosion located on the palate, what could this be? how could you tell?
recurrent HSV, atypical epithelial cells and tzanck cells would be noted
RECURRENT APHTHOUS STOMATITIS stages
Clinical Forms of Recurrent
Aphthous Stomatitis
minor
major
herpetiform
where do recurrent aphthous stomatitis lesions occur?
non-keratinized, moveable tissue
most likely?
Minor Recurrent Aphthous Stomatitis
most likely?
Major Recurrent Aphthous Stomatitis
most likely?
Herpetiform Recurrent Aphthous Stomatitis
durations and sizes of the dif forms of recurrent aphthous stomatitis
- Minor: small, resolve 10-14d
- Major: large, can last months
- Herpetiform: many small in clusters, 10-14d with frequent recurrence
Aphthous-like Lesions
Associated Systemic Diseases
- Behcet’s Syndrome
- Reiter’s Syndrome (reactive arthritis)
- Inflammatory Bowel Disease– Ulcerative colitis/ Crohn’s Disease
- Malabsorption Syndromes– Gluten Sensitive Enteropathy
- Cyclic Neutropenia
- HIV / AIDS
candidasis
C. Albicans part of normal flora, result of dysbiosis
can be coinfection with staph as well
wiped off with red base, form of candidasis?
pseudomembraneous
forms candidasis
pseudomembraneous
atrophic
hyperplastic
angular chelitis
CENTRAL PAPILLARY ATROPHY/ MEDIAN RHOMBOID GLOSSITIS
likely form candidasis
atrophic/ erthymatous
angular chelitis
occurs at corners due to loss of OVD,
hyperplastic candidasis app
leukoplakia on the buccal mucosa, biopsy would reveal C. Alb
CENTRAL PAPILLARY ATROPHY
MEDIAN RHOMBOID GLOSSITIS
form of candidasis, occurs on dorsum of tongue
CENTRAL PAPILLARY ATROPHY
MEDIAN RHOMBOID GLOSSITIS
pt states they wear dentures almost 24/7 what could this be?
atrophic candidasis
MUCOCELE
due to mucus accum in salivary gland ducts
presents as an soft tissue mass
ranula
mucocele at the SM gland
soft palpation, what could this be?
ranula
Types of Gingivitis
- Plaque-associated gingivitis
- NUG
- Medication-induced gingivitis – Drug-related gingival hyperplasia
- Allergic gingivitis– Plasma cell gingivitis
- Specific infection-related gingivitis– HSV
- Dermatosis-related gingivitis– Desquamative gingivitis
describe
gingivitis, diffuse erythema
possible ulcer on attached mucosa=recurrent HSV
NUG presentation
interdental papilla punched out/necrosed
Periodontitis as a Manifestation of Systemic Disease
- Diabetes mellitus
- HIV infection
- Decreased numbers of leukocytes– Neutropenia
- Leukocyte dysfunction syndromes
- Papillon-Lefevre Syndrome
PERICORONITIS
most common where?
most common at 3rd molars due to excess tissue= nidus for debris allowing inflam
FOLIATE PAPILLAE AND LINGUAL TONSILS
often mistaken for pathology
FOLIATE PAPILLAE AND LINGUAL TONSILS
ORAL LYMPHOEPITHELIAL CYST histo
lymphoid proliferation in the conn tissue wall with a strat sqaumous cyst lining
ORAL LYMPHOEPITHELIAL CYST app
may be a yellowish submuscosal bulge
fissured tongues
not pathologic, maintenence req to keep healthy
Hairy Tongue
* what is this?
* Exogenous pigmentation?
* associated factors?
- Elongated filliform papillae
- Exogenous pigmentation may impart a brown or black appearance
- Various associated factors
– Heavy smoking
– Antibiotic therapy
hairy tongue
what is likely here?
hairy tongue
Fordyce Granules
- Ectopic sebaceous glands, yellowish submucosal papules
- Development stimulated at puberty
- often bilateral
- not pathologic, no bioipsy needed
most likley?
fordyce granules