developmental and odontogenic cysts day 2 Flashcards

1
Q

“Globulomaxillary Cyst”
location?
why is this odd?

A
  • The globulomaxillary position is located at the junction of maxilla with premaxilla, between maxillary lateral incisor and canine
  • No developmental fissural cyst in this position
  • A developmental “globulomaxillary cyst” does not exist
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2
Q

Globulomaxillary Position

A
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3
Q

globulomaxillary cyst radio

A

presents as a well enscribed lucency in C/LI region, may be at apex or lateral

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4
Q

cyst in globularmaxillary region can cause what?

A

root divergence

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5
Q

Globulomaxillary Lesions likely dx’s

A
  • Periapical cyst 50%
  • Periapical granuloma 15%
  • Lateral periodontal cyst 10%
  • Odontogenic keratocyst 10%
  • Giant cell tumor 7%
  • Other lesions 3%
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6
Q

central vs perihperal lesions

A

central: arise in bone
peripheral: arise outside the bone

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7
Q

other lesions that can also present as globulomaxillary findings

A

combined 3% probability for these
* Gorlin cyst
* Odontogenic myxoma
* Adenomatoid odontogenic tumor
* Neurofibroma
* Hemangioma

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8
Q

types of DENTAL LAMINA CYSTS

A

Lateral Periodontal Cyst
Botryoid Odontogenic Cyst
Gingiva Cyst of Adult
Dental Lamina Cyst of Newborn

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9
Q

Lateral Periodontal Cyst
arises from?
teeth? predominant demo?
common areas?

A
  • A developmental cyst that arises from dental lamina rests (rests of Serres)
  • Vital teeth of adult males (3:1)
  • Mandibular premolar area most commonly
  • Maxillary incisor-canine area
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10
Q

dev cyst and inflamm

A

usually none unless infected

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11
Q

epi lining of lat perio cyst

A

alternating thin and thick strat squamous lining

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12
Q

lateral periodontal cyst radiograph

A

well circumscribed, unilocular radiolucency at lateral aspect at most often vital man PM

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13
Q

Botryoid Odontogenic Cyst
usually presents as?

A
  • Polycystic variant of the lateral periodontal cyst
  • A developmental odontogenic cyst that presents as a multilocular lucency associated with the vital mandibular premolars of adults
  • usually found in same areas as lat perio cyst
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14
Q

botryoid vs lat perio cyst

A

multi vs unilocular lucencies

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15
Q

Botryoid Odontogenic Cyst radio

A

multilocular lucency

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16
Q

Gingival Cysts
* arises from?
* teeth/demo?
* locations?

A
  • Soft tissue counterpart of the lateral periodontal cyst
  • A developmental cyst that arises from dental lamina rests
    (rests of Serres)
  • Vital teeth of adult males (3:1)
  • Mandibular premolar area and maxillary incisor-canine area
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17
Q

gingival cyst radio

A

not present, entirely in soft tissue

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18
Q

coloration gingival cyst?

A

bluish possible

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19
Q

bone with gingival cyst

A

can have pressure resorbtion

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20
Q

gingival cyst histo

A

alt patterns of thin thick epi, also oral mucosa opposite of lumen

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21
Q

Dental Lamina
Cyst of Newborn

A

small gingival/alveolar bumps, app whitish

22
Q

dental lamina cyst of newborn tx

A

no need, usually subside

23
Q

dental lamina cyst of new born histo

A

many cystic areas filled with keratin with thin epi lining

24
Q

palatal cyst of newborns

A

bohns nodules and epstein pearls

25
Cyst of Newborn types
* Dental lamina cysts - epithelial remnants of dental lamina from odontogenesis, occur on alveolar ridge= Odontogenic cysts * Epstein’s pearls - epithelial remnants from palatal shelf fusion at midline = Non-odontogenic cysts * Bohn’s nodules - epithelial remnants from minor salivary gland formation, all over palate =Non-odontogenic cysts
26
palatal cyst of newborns histo
all identical, class based on location
27
Primordial Cyst likely to be?
* Radiographic term for a cyst that develops in place of a tooth, tooth not present (congenitally missing) * Likely to be an Odontogenic Keratocyst (OKC)
28
primordial cyst radio
typically a well defined unilocular lucency at posterior mandible
29
Odontogenic Keratocyst (OKC) demo? location? growth? recurrence? radio?
* Posterior jaws (mandible) of teenagers, young adults * Aggressive growth with 30% recurrence (high) * A unilocular or multilocular radiolucency; imitates other lucencies
30
OKC distribution
31
Radiographic Presentations OKC, %
* Primordial cysts 50% * Lateral periodontal 25% * Dentigerous 10% * Globulomaxillary 10%
32
assume tooth is vital, what could this be?
OKC lat perio cyst odontogenic fibroma
33
what could this be? describe it?
well defined, multilocular lucency dentigerous cyst OKC ameloblastic fibroma odontogenic fibroma
34
what could this be, describe it?
well defined, unilocular radioluceny OKC residual cyst primordial cyst
35
what could this lesion be? tooth is vital
lateral periodontal cyst OKC
36
Extra-Osseous (peripheral) Odontogenic Keratocyst (OKC)
can also occur outside bone as a soft tissue lesion (bump on gum)
37
Extra-Osseous (peripheral) Odontogenic Keratocyst (OKC) radio
none, soft tissue involved only
38
Odontogenic Keratocyst Histology
* Compact epithelium, no rete ridges, 8 to 10 cell layers thick * Corrugated surface parakeratin *** Prominent, palisaded, hyperchromatic basal layer** lots of keratin in lumen
39
bipsy from posterior mandible cyst, what could this be? what would high power of the basale layer show to confirm?
OKC: keratin in lumen with a hyperchromic palisaded basale layer
40
why do OKC recur often?
daughter cysts present, usually locasted in conn tissue wall of the main cyst that is excised
41
Significance of the Odontogenic Keratocyst * behavior? * Recurrence rate? * associated Syndrome?
* Aggressive behavior * Recurrence - 30% * Nevoid Basal Cell Carcinoma Syndrome
42
Clinical Settings Odontogenic Keratocyst
* Non-syndrome-associated OKC - idiopathic * Syndrome-associated OKC –multiple OKCs common in the nevoid basal cell carcinoma syndrome
43
Nevoid Basal Cell Carcinoma Syndrome additional names
* Basal cell nevus syndrome * Gorlin-Goltz syndrome * Gorlin syndrome
44
gorlin syndrome inheritence/genetic behavior
AD- highly penetrant and varible expression
45
basal cell nevus syndrome mutation
* Mutation in PTCH (PATCHED) tumor supressor gene at 9q22.3
46
Nevoid Basal Cell Carcinoma Syndrome signs
* Skeletal anomalies: Bifid ribs * Jaw cysts: Multiple OKCs * Skin tumors: Multiple, early onset basal cell carcinomas * Neoplasms: CNS –Medulloblastoma
47
multiple OKCs ID'd what could this be?
nevoid basal cell carcinoma syndrome
48
an individual present with multiple BCCa's and this image, what is possible?
gorlin syndrome
49
BCCa's of gorlin-goltz syndrome
multiple possible early in life
50
palms of gorlin syndrome pts
may have indentations
51
falx cerebri with gorlin syndrome
can become calcified
52
Early Recognition and Diagnosis of Nevoid Basal Cell Carcinoma Syndrome
* OKCs present early * Prevent disfiguring basal cell carcinomas * Evaluate for medulloblastoma