Development Of The peripheral Nervous System (EMB) Flashcards
Where is the division where we will have brain and SC
Above is what and below is what
4th somite
Above is brain, below is SC
What is gray matter made up of
Dorsal horn
Lateral horn
Anterior horn
Cells bodies in gray matter are not what
Mylenated
Dorsal horn is what type of neurons
Sensory
Gray Lateral horn is what type of neurons and what location
T1 - L2
Autonomic neurons
What neurons are in anterior horn
Motor neurons
The gray mater houses what in terms of neurons
The cell bodies
The white matter houses what in terms of neurons
The axons
The lateral horn of the white matter houses what
Sensory and motor neurons
What is developed in the alar plate
Sensory neurons that are contained in CNS and never leave
The basal plate gives rise to what
Motor neurons
Sensory neurons is what type of neurons?
Afferent neurons
What are the three zones of the developing spinal cord
- Ventricular zone
- Intermediate zone - gray matter
- Marginal zone - white matter
What does the intermediate zone give rise to
The gray matter
What does the marginal zone give rise to
The white matter
What cells are located in ventricular zone
Cells that make CSF
What cells are located in intermediate zone
Astrocytes, give rise to gray matter
What cells are located in marginal zone
Axons and oligodendrocytes (that mylenate)
Oligodendrocytes come from what
Neural crest cells
Microglial cells come from what
Mesoderm
What comes from neuroectoderm
Astocytes
Oligodendrocytes
Dendrites and axons
Where is the cord in a newborn found
L2/L3
Where is cord in adult found
L1/L2
Neural crest cells give rise to what
Spinal ganglion and sensory neurons in the periphery
Dorsal spinal cord is what type of neurons
Sensory
Ventral spinal cord neurons are what type of cells
Motor neurons
BMP makes cells into what
Dorsal neurons
SHH makes cells into what
Ventral neurons
BMP activates what
PAX3 and PAX 7 which make the alar plate
SHH activate what
NKX 2.2 and NKX 6.1 and the formation of the basal plate
What two things form the PNS
The neural crest and ectodermal placode
What PNS cells develop from neural tube
Motor neurons
Pre-glangionic autonomic neurons
What PNS cells develop from neural crest cells
Neurons of dorsal root ganglia
Sensory ganglia of cranial neves
Schwann cells
Sympathetic ganglia
Parasympathetic ganglia
The dorsal root comes from what
Neural crest cells
The ventral root comes from what
Neural ectoderm cells
The spinal nerve contains what types of cells
Both sensory and motor, thus come from NC and NE
General somatic efferent neurons
What are they and where do they come from
Somatic muscle
From NE
General visceral efferent neurons
What are they and where do they come from
Autonomic neurons to smooth and cardiac muscle and glands
From NE
Special visceral efferent
What are they and where do they come from
Neurons that innervate muscles derived from the pharyngeal arches
From the NE
General somatic afferent neurons
What are they and where do they come from
Sensory in the skin, joints and tendons
From NC
General visceral afferent neurons
Sensory of the visceral structures
From the NC
Special somatic afferent neurons
What are they and where do they come from
Hearing, balance, and sight
Special visceral afferent neurons
Taste, smell, chemical senses
Come from cranial nerves
Post-ganglionic ANS cells come from what
Neural crest
ANS pre-ganglionic cells come from what
Neuroectoderm
The preganglionic fibers form what
Spinal cord to sympathetic ganglia
Are preganglionic fibers myelonated?
Yes
Postganglionic fibers form what
Ganglia to vicera
Preganglia are long or short?
Long
Postganglionnic fibers are what
Short and nonmylenated
The anterior nerve roots are what type of nerves?
Motor neurons (efferent)
The posterior roots are what types of nerves?
Sensory neurons (afferent)
The grey matter is comprised of what
The nerves cell bodies (CNS)
The white matter is comprised of what
The axons that are usually mylenated with schwann cells (PNS)
The posterior and anterior nerve roots untie where to form what
Unite proximal to the intervertebral foramen to form a mixed spinal nerve (motor and sensory)
What type of neurons do posterior and anterior rami carry?
Both sensory and motor neurons.
What are general sensory fibers
General somatic afferent fibers
Transmit sensation from the body to the CNS
What are somatic motor fibers [GSE]
General somatic efferent fibers
Transmit impulses to skeletal muscles (voluntary)
What are visceral sensory fibers [GVA]
General visceral afferent fibers
Transmit pain or subconscious visceral reflex sensations
What are visceral motor fibers [GVE]
General visceral efferent fibers
Transmit impulses to smooth (involuntary)muscle and glandulary tissue