Development of the great vessels Flashcards
Sinus venosus –> sinus venarum in an adult
Right atrium (sinus of vena cava, smooth)
Sinus venosus in an adult
Vena cava (exp SVC) Coronary sinus
Primordial atrium in an adult
Right and left auricles
Pulmonary veins in an adult
Left atrium (smooth)
Primordial ventricle in an adult
Left ventricle
Bulbus cordis - proximal 1/3 in an adult
right ventricle
Bulbus cordis - middle 1/3 (conus cordis) in an adult
Infundibulum (RV) and aortic vestibule
Bulbus cordis - distal 1/3 (trunks arteriosus) in an adult
roots and proximal parts of pulmonary trunk and aorta
Aortic sac in an adult
proximal aortic arch and proximal brachiocephalic trunk
What does the right 3rd arch form
right common carotid artery
right internal carotid artery
What does the left 3rd arch form?
left common carotid artery
left internal carotid artery
What does the 4th right arch form?
right proximal subclavian artery
What does the 4th left arch form?
aortic arch (middle)
What does the 6th right arch form?
right pulmonary artery
What does the 6th left arch form?
left pulmonary artery
ductus arteriosus
What does the right 7th IS artery form?
right distal subclavian artery
What does the left 7th IS artery form?
left subclavian artery
What does the right dorsal aorta form?
right distal subclavian artery
What does the left dorsal aorta form?
descending aorta (distal aortic arch)
Embryology and cause of patent foramen ovale
Foramen vale is a defect on septum secundum, which is connected with osmium secundum (on septum primum)
Caused by failure of fusion of either results in patent foramen ovale
Embryology and cause of patent ductus arteriosus
Ductus arteriosus is the connection between 6th aortic arch and left dorsal aorta. After full development, it extends between pulmonary trunk and aorta (distal to the origin of the left subclavian artery)
No clear cause; chromosomal abnormalities, prematurity, low birth weight, prostaglandins, high altitude and low atmospheric oxygen tension, hypoxia
Embryology and cause of atrial septal defect (osmium primum defect is a form of ASD)
IA septum is formed by septum primum and septum secundum
Caused by failure of proper development of septum secundum OR failure of closure of ostium primum
Embryology and cause of ventricular septal defect (most common)
IV septum is derived from endocardial cushion (membranous) and walls of primordial ventricle and bulbs cordis (muscular)
Caused by a defect in either the membranous (more common) or muscular portion of IV septum
or failure of fusion of membranous muscular portions
Embryology and cause of Tetralogy of Fallot (VSD, pulmonary artery stenosis, deviation if the aortic origin to the right (overriding aorta), hypertrophy of RV)
Caused by unequal division of conus cord with resultant anterior displacement (malalignment) of the aorticopulmonary septum
Embryology and cause of Transpotition of the great vessels
Caused by failure of the articopulmonary (conotruncal) septum to spiral
Embryology and cause of coarctation of the aorta (narrowing of the aorta, usually distal to the origin of the left subclavian artery from the arch of aorta
No clear cause; contraction of ductus arteriosus
